8 citations,
December 2022 in “Regenerative Therapy” New regenerative treatments for hair loss show promise but need more research for confirmation.
7 citations,
January 2022 in “Plants” Rice husk and bran extracts from the Bue Bang 3 CMU variety can potentially treat hair loss due to their antioxidant, anti-inflammatory, and anti-androgenic properties.
1 citations,
December 2022 in “Current Issues in Molecular Biology” Annurca apple extract improved hair growth in mice and could potentially prevent hair loss.
1 citations,
March 2022 in “Daehanhanuihakoeji” Artemisia sieversiana extract may help prevent hair loss and promote hair growth.
1 citations,
August 2016 in “Hanbang an'i'bi'in'hu pibu'gwa haghoeji” YangHyulEum Gami-Bang extract may help treat hair loss.
August 2024 in “Cosmetics” Peanut callus extract helps grow hair and prevent hair loss.
February 2024 in “International Journal of Molecular Sciences” Hair loss in Androgenetic Alopecia is caused by genetics, aging, and lifestyle, leading to hair follicle shrinkage and related health risks.
June 2023 in “Drugs & Therapy Perspectives” New treatments for male pattern hair loss look promising, but established treatments are still the main option.
January 2023 in “Applied sciences” Equisetum debile extracts may help with skin whitening, anti-wrinkle, and anti-hair loss treatments.
16 citations,
April 2017 in “Journal of Cosmetic Dermatology” Ficus carica leaf extract may help treat skin disorders by reducing inflammation and androgen effects in skin cells.
7 citations,
January 1981 in “Springer eBooks” The document concludes that hair biology is complex and there are still unanswered questions about hair loss and follicle changes.
August 2024 in “Cosmetics” Personalized treatments for hair loss are becoming more effective by using genetic information.
Avicennia marina extract and avicequinone C can potentially promote hair growth and treat hair loss by interfering with hair loss mechanisms and boosting growth factors.
39 citations,
April 2018 in “Hormones” No consistent link between genotype and phenotype in 5-α-Reductase type 2 deficiency.
37 citations,
January 2009 in “Sexual Development” Fadrozole and Finasteride change frog sex ratios and cause intersex animals with altered gene expressions.
49 citations,
August 2009 in “British Journal of Cancer” Finasteride might lower the risk of low-grade prostate cancer but not high-grade cancer, while alpha-blockers might reduce high-grade cancer risk.
45 citations,
March 2005 in “Steroids” Four new compounds were more effective than finasteride in treating prostate issues and hair loss, with one being 100 times more active and safe for use.
44 citations,
October 2010 in “BJUI” 5-α-reductase inhibitors reduce prostate cancer risk but may cause sexual dysfunction and don't affect high-grade tumor or death rates.
30 citations,
October 2020 in “Nature Communications” Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.
29 citations,
April 2019 in “Lasers in Medical Science” Laser and minoxidil combo promotes better hair growth than minoxidil alone, safely.
15 citations,
December 2016 in “Steroids” Researchers developed a new method to find substances in herbs that can block a specific enzyme linked to hair loss.
72 citations,
January 2011 in “Current Pharmaceutical Design” S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.
45 citations,
August 2010 in “Hormone Molecular Biology and Clinical Investigation” Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.
36 citations,
June 2014 in “International Journal of Dermatology” Dutasteride helps hair growth in those unresponsive to finasteride, but may cause more sexual dysfunction.
34 citations,
February 1993 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.
33 citations,
June 2015 in “Current Opinion in Endocrinology, Diabetes and Obesity” 5α reductase inhibitors treat hair loss but may cause sexual side effects and risks.
30 citations,
December 2017 in “Medical Hypotheses” The model suggests that scalp tension could lead to hair loss, with factors like blood vessel hardening, enlarged oil glands, and poor microcirculation also playing a role. It also hints at a possible link between skull shape and baldness pattern.
27 citations,
October 2015 in “Neuropharmacology” Dutasteride protects dopamine neurons in Parkinson's mice, but Finasteride doesn't.
26 citations,
June 2005 in “Journal of Molecular Endocrinology” Dutasteride is more efficient than finasteride, but individual results vary.
18 citations,
March 2020 in “Frontiers in Neuroendocrinology” The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.