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Testosterone and dihydrotestosterone treatments can help with penile growth in males with 5α-reductase type 2 deficiency, with dihydrotestosterone being more effective in infancy.

Finasteride exposure in pregnancy causes genital abnormalities in male rats.

Using finasteride or dutasteride may cause long-lasting erectile dysfunction.

High doses of finasteride cause cell growth and tumors in mice.

Finasteride causes abnormal growth in male mice cells at high doses.

Pueraria mirifica extract may help treat benign prostatic hyperplasia.

Glioblastoma cells can make androgens, which might help the tumor grow.

Dutasteride is the most effective hair loss treatment after 24 weeks, but finasteride leads to the most hair growth after 48 weeks.

Androgen treatment with dihydrotestosterone may help maintain height in patients with 5-α-reductase type 2 deficiency, especially before puberty.

5α-reductase inhibitors help shrink the prostate, improve urinary symptoms, and may reduce prostate cancer risk.

All five human steroid 5α-reductase enzymes are found in the endoplasmic reticulum.

Cimicifuga racemosa extract may help prevent and treat prostate issues by inhibiting 5α-reductase.

5α-reductase inhibitors like finasteride and dutasteride can help treat skin disorders stimulated by androgens, such as hair loss and acne.

BB4CMU rice bran oil may help treat hair loss and gray hair.

Dutasteride may help treat prostate cancer by causing cancer cells to shrink and die.

Compound 4 is a promising treatment for hair loss with low toxicity.

Dutasteride may help protect neurons and reduce inflammation in Parkinson's disease.

Dutasteride improved both hair loss and acne in two young men.

Dutasteride more effectively lowers DHT levels in men with enlarged prostates than finasteride.

Neuroactive steroids and the enzyme 5α-reductase might be involved in the development of Tourette's syndrome.

Minoxidil may help treat hair loss by reducing the activity of a specific enzyme linked to baldness.

Ficus benghalensis leaf extracts can effectively promote hair growth and inhibit hair loss.

Eriocitrin and silymarin might be effective for hair loss treatment and need more research.

Three siblings with a rare genetic condition had abnormal sexual development and chose different gender identities, needing surgery and therapy.

A microemulsion with Carthamus tinctorius extract effectively inhibits 5α-reductase and improves skin and hair follicle delivery.

Men with early balding showed higher levels of certain genes linked to hair loss and possibly prostate cancer.

Trapa bispinosa Roxb. extract may help reduce prostate size and cell growth in BPH.

5α-reductase inhibitors can interfere with doping tests by masking banned substances.

Finasteride and dutasteride effectively treat hair loss in men and women, but may cause side effects like low libido and depression.

Saw palmetto berries might help with hair growth.