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The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Taking 5-alpha reductase inhibitors might be linked to breast cancer in men.

5α-reductase inhibitors and alpha-1 adrenergic antagonists together effectively treat benign prostatic hyperplasia, with long-term benefits.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Inhibitors of the enzyme 5 alpha-reductase could potentially treat disorders like prostate cancer and baldness.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

5-alpha reductase deficiency leads to male sexual development issues and treatments like finasteride help with prostate enlargement and hair loss.

Using finasteride or dutasteride does not increase the risk of male breast cancer.

Finasteride doesn't affect erections much, but may decrease libido in men.

Hair loss drugs may cause sexual issues and infertility in men.

Plant-based compounds might be effective, low-side-effect treatments for prostate cancer by blocking a specific enzyme.

Finasteride does not negatively affect male reproductive function.

Finasteride improves heart function in obese and aging male rats by reducing oxidative stress and p53 protein levels.

Natural 5AR inhibitors effectively improve mild to moderate hair loss in men.

The new saw palmetto extract effectively inhibits an enzyme linked to prostate enlargement and may be as good as standard treatments.

New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.

Accurate protein modeling can help develop new treatments for prostate cancer and other diseases.

Plant extracts effectively reduce hair loss and increase growth, offering a safe alternative treatment.

Eclipta alba extract could be a promising natural treatment for hair loss.

The β-sitosterol hair gel is effective and promising for treating hair loss.

Blocking the enzyme that turns testosterone into DHT can safely and effectively treat enlarged prostate.

Drugs that block DHT production can effectively treat enlarged prostate and improve urinary issues with some sexual side effects.

5α-reductase inhibitors may prevent prostate cancer but could also raise the risk of more severe cancers.

Testosterone's muscle-building effects do not require its conversion to DHT.

Men over 66 taking medication for prostate enlargement have a higher risk of depression and self-harm, especially in the first 18 months of treatment.

5α-reductase inhibitors increase the risk of sexual dysfunction, especially in men with enlarged prostate.

Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

Long-term use of a certain medication can worsen erectile function in aged rats by damaging penile muscle cells.

Curcuma aeruginosa extract combined with minoxidil effectively treats male-pattern baldness.

New compounds may soon be tested to treat excessive hair growth in women.