research Hormonal Effects on Hair Follicles
Hormones like testosterone and estrogen significantly affect hair growth and structure.
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research Hair: What Is New in Diagnosis and Management?
Female pattern hair loss diagnosed by scalp appearance, treated with combined therapies and targeted approaches.
research Hair Loss and Herbs for Treatment
Herbs can potentially treat hair loss by inhibiting a key enzyme and promoting hair growth, and deficiencies in zinc, biotin, and iron are linked to hair loss.
research Identification of Anabolic Selective Androgen Receptor Modulators with Reduced Activities in Reproductive Tissues and Sebaceous Glands
Two new compounds were found to build bone and muscle without affecting reproductive organs and skin oil glands.
research Platycladus Orientalis Leaves: A Systematic Review on Botany, Phytochemistry, and Pharmacology
The leaves of Platycladus orientalis have potential health benefits but require more research for safety and understanding how they work.
research Promotion Effect of Apo-9'-Fucoxanthinone from Sargassum Muticum on Hair Growth via the Activation of Wnt/β-Catenin and VEGF-R2
Sargassum muticum extract and its component apo-9'-fucoxanthinone may help hair growth and treat hair loss.
research Male Androgenetic Alopecia: Medical and Surgical Treatments
Finasteride effectively treats male hair loss, increasing length and thickness.
research Hairless or Fertile? Finasteride Leads to Epididymal Changes and Infertility in Rats
Finasteride may cause infertility in rats by affecting epididymis and sperm function.
research Finasteride And Dutasteride In The Treatment Of Androgenetic Alopecia: Risk Or Benefit?
Finasteride and dutasteride may help prevent hair loss but could cause side effects like sexual dysfunction and psychological issues.
research 5-Alpha-Reductase Inhibitors for Prostate Cancer Chemoprevention: An Updated Cochrane Systematic Review
5-α-reductase inhibitors reduce prostate cancer risk but may cause sexual dysfunction and don't affect high-grade tumor or death rates.
research Evidence for Increased 5α-Reductase Activity During Early Childhood in Daughters of Women With Polycystic Ovary Syndrome
Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.
research Inhibition of 5α-Reductase Impairs Cognitive Performance, Alters Dendritic Morphology, and Increases Tau Phosphorylation in the Hippocampus of Male 3xTg-AD Mice
Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.
research Clinical Trial and In Vitro Study Investigating Topical Application of Zataria Multiflora Boiss. and Matricaria Chamomilla Extracts for Androgenetic Alopecia
Extracts improve hair growth in alopecia.
research Androgenic Hormone Profile in Patients with Androgenetic Alopecia
People with hair loss have different hormone levels, and these hormones can affect hair growth.
research Frontal Fibrosing Alopecia: A Review and Practical Guide for Clinicians
The article concludes that understanding Frontal Fibrosing Alopecia (FFA) is crucial for effective treatment, which includes medication like 5α-reductase inhibitors and hydroxychloroquine.
research Safety Concerns When Using Novel Medications to Treat Alopecia
Consider benefits and risks of new alopecia treatments for safety.
research Benign Prostatic Hyperplasia And Male Lower Urinary Symptoms: A Guide For Family Physicians
Family doctors can manage older men with urinary symptoms using exams, tests, and medications.
research 5α-Reductase Inhibitory Components as Antiandrogens From Herbal Medicine
A plant extract was found to effectively block an enzyme related to male hormone-related diseases.
research Unknown Safety Profile of Ingredients in Hair Supplements: A Call to Action for Improved Patient Safety
The conclusion is that hair supplement ingredients may be unsafe and should be disclosed and proven safe before use.
research The Relationship Between Mental Health and Drugs Used in Dermatology
Some skin medication can rarely cause or worsen mental health issues; knowing this is important because mental health problems are increasing worldwide.
research Recommendations on the Clinical Management of Androgenetic Alopecia: A Consensus Document from the Spanish Group of Trichology of the Spanish Academy of Dermatology and Venereology
Dermatologists recommend oral dutasteride for male hair loss, low-dose oral minoxidil for female hair loss, and a multidisciplinary approach for young patients, with caution during pregnancy.
research Synthesis and Application of Clinically Approved Small-Molecule Drugs Targeting Androgen Receptor
Drugs targeting the Androgen Receptor are effective for treating prostate cancer and other androgen-related conditions.
research Androgenetic Alopecia as a Cardiovascular Risk Factor
Hair loss may increase heart disease risk.
research 5α-Reductase Inhibitors: Progress and Therapeutic Potential
5α-reductase inhibitors help treat disorders caused by DHT and have potential for future therapies.
research Marked Suppression of Dihydrotestosterone in Men with Benign Prostatic Hyperplasia by Dutasteride, a Dual 5α-Reductase Inhibitor
Dutasteride more effectively lowers DHT levels in men with enlarged prostates than finasteride.
research Other Antiandrogens: Alternative Treatments for Acne and Hirsutism
Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.
research Identification of Beta-Sitosterol and Stigmasterol as Possible Inhibitors of 5 Alpha-Reductase 1: An In-Silico Study
Beta-sitosterol and stigmasterol might help prevent hair loss by blocking a specific enzyme.
research Finasteride: The First 5 Alpha-Reductase Inhibitor
research Efficacy and Safety of a New 5% Minoxidil Formulation in Male Androgenetic Alopecia: A Randomized, Placebo-Controlled, Double-Blind, Noninferiority Study
New 5% minoxidil formula safely and effectively treats male hair loss.
research Clinical Pearls in Dermatology 2013
The document gives treatment advice for various skin conditions, like using metronidazole for perioral dermatitis and minoxidil for hair loss.