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The document concludes that sexual and psychiatric side effects from 5-alpha-reductase inhibitors are reported, but more high-quality research is needed to understand how often they occur.

Rats had lasting erectile problems after stopping a certain medication.

Some new progesterone derivatives are better at blocking testosterone conversion than a common drug.

5 alpha-reductase inhibitors can slightly improve symptoms of enlarged prostate but have a high risk of sexual side effects.

Finasteride and dutasteride are effective for long-term treatment of enlarged prostates but have sexual side effects and a risk of high-grade prostate cancer.

Men using hair loss drugs like finasteride may experience sexual side effects like erectile dysfunction, but it's unclear who will be affected and when. Treating depression and sexual symptoms is suggested, as these men often have higher rates of both. More research is needed to understand why these side effects occur.

Taking 5-Alpha Reductase Inhibitors before bladder removal surgery might make high-grade bladder tumors less aggressive.

Dutasteride effectively and safely treats male hair loss for over a year.

5-alpha reductase inhibitors can cause sexual, neurologic, endocrine, and cardiovascular side effects, but these are rare and usually stop after ending treatment.

Medicines for enlarged prostate may raise the risk of breast growth and tenderness but not breast cancer.

Black pepper leaf extract contains compounds that can block testosterone effects and promote hair growth.

Using 5-alpha-reductase inhibitors may improve bladder cancer survival in men.

The developed model can predict effective 5-alpha-reductase enzyme inhibitors.

The human type II 5α-reductase gene, linked to certain male health conditions, has a specific structure and low similarity to other related genes.

5-alpha reductase inhibitors might worsen lung recovery in COVID-19 patients, suggesting a pause in their use.

The human type II 5α-reductase gene has a specific structure important for understanding certain medical conditions.

Certain Dibenzo derivatives may help treat prostate cancer.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Finasteride effectively treats hair loss and prostate issues with minimal side effects.

Dihydrotestosterone and 5α-Reductase play a role in hair loss and prostate health, and finasteride can increase hair growth in men without affecting sperm production, but it doesn't work for postmenopausal women with hair loss.

Finasteride and minoxidil together promote hair growth better than either alone.

Taking finasteride pills and using minoxidil lotion together can help grow hair.

5-alpha-reductase inhibitors can lower prostate cancer risk but may increase high-grade tumors and cause sexual side effects.

Low-dose dutasteride effectively and safely promotes hair growth in men with androgenetic alopecia.

Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

Starting 5-alpha reductase inhibitors does not significantly increase the risk of rhabdomyolysis in older men, but is linked to a higher risk of muscle conditions.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

5-alpha-reductase inhibitors may cause a low incidence of erectile dysfunction that decreases over time.

Using 5 alpha reductase inhibitors may increase dementia risk in the first two years.