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Ageratum conyzoides L. extract may effectively and safely treat hair loss.

Vitamin E affects liver metabolism, enhancing stress resistance, reducing blood clotting, and altering hormone processing.

5α-reductase inhibitors increase the risk of sexual dysfunction, especially in men with enlarged prostate.

Equisetum debile extract, especially the ethyl acetate type, may be a promising natural ingredient for anti-hair loss products.

Taking 5α-reductase inhibitors does not significantly increase the risk of breast cancer in men.

Compounds from the plant Mammea siamensis may help treat hair loss.

α-Blockers and 5-ARIs for BPH can cause sexual dysfunction, including erectile and ejaculatory issues.

Some vegetables from Northern Thailand show promise for health benefits, including hair loss treatment and antioxidant properties.

Chinese medicine may help treat hair loss by affecting genes and enzyme activity.

Cauliflower Mushroom extract may help treat male hair loss by affecting hair growth-related genes.

Puerariae Flos extract may help treat hair loss by blocking a hair loss-related enzyme and promoting hair growth.

The enzyme type 1 5α-reductase is more active in the hair follicle's lower part than in the skin's outer layer.

Cimicifuga racemosa extract may help prevent and treat prostate issues by inhibiting 5α-reductase.

5α-reductase inhibitors help shrink the prostate, improve urinary symptoms, and may reduce prostate cancer risk.

Dutasteride reduces DHT more effectively than finasteride.

Compound 4 is a promising treatment for hair loss with low toxicity.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

Three siblings with a rare genetic condition had abnormal sexual development and chose different gender identities, needing surgery and therapy.

Dutasteride improved both hair loss and acne in two young men.

Finasteride exposure in pregnancy causes genital abnormalities in male rats.

Male yak hair growth is influenced by DHT synthesis, which is promoted by 5α-red1 and AR during growth phases, while E2 may inhibit growth through ERα.

The study found that the enzyme linked to acne is present in the same areas of both acne-affected and normal skin.

Compound 7b is a promising candidate for treating benign prostatic hyperplasia and prostate cancer.

Male pattern baldness involves three mechanisms and finasteride can help reverse it.

Minoxidil, finasteride, and low-level laser light therapy are effective FDA-approved treatments for hair loss.

Finasteride may increase depression by reducing brain cell growth.

Finasteride helps treat hair loss by blocking enzyme activity.

The study created a model to help design new inhibitors for steroidal 5α-reductase enzymes.

Dutasteride caused more penile tissue changes than finasteride, possibly increasing erectile dysfunction risk.

Compounds 4, 4b, and 4c effectively inhibit an enzyme linked to testosterone conversion without significant toxicity.