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A mix of methotrexate, corticosteroids, and topical minoxidil effectively treated severe total body hair loss, but caused stretch marks and needs long-term monitoring.

Higher doses of isotretinoin may lead to more hair loss.

Isotretinoin is safe and effective for acne, with common side effects like dry lips; serious side effects are rare.

Asiasari radix extract may relieve certain types of pain by affecting GABA and NMDA receptors.

Tet2 and Tet3 enzymes are important for controlling hair growth and shape by affecting gene activity and DNA structure in hair follicles.

The tropical legume Sesbania rostrata can form nodules in waterlogged conditions using a different method that involves plant hormones and specific genes.

The enzymes Tet2 and Tet3 are important for skin cell development and hair growth.

Phospholipase A2 enzymes play key roles in skin health and disease.

People with vitiligo may have a lower risk of heart disease.

Storing hair follicles in special buffers with added protective substances can increase hair growth and reduce cell death.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

Liposomes improve drug delivery and reduce skin irritation in dermatology.

Trichohyalin is modified by enzymes to form strong structures in hair cells.

Different soft tissue fillers can cause various skin reactions; biodegradable fillers are safer and non-biodegradable ones like silicone can lead to long-term problems.

Defective mitochondrial DNA replication causes aging symptoms and increased oxidative damage in mice.

Ketoconazole reduced hair growth and improved acne in women, but caused side effects needing careful monitoring.

Male hormones, or androgens, affect women's health in areas like mood and bone density, and hormone replacement therapy using antiandrogenic progestogens can improve mood disorders and alertness in menopausal women.

Scalp cooling is largely ineffective in preventing hair loss from breast cancer chemotherapy.

Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.

An enzyme other than TNAP might be responsible for vitamin B-6 metabolism in the skin.

The document concludes that understanding hair follicles requires more research using computational methods and an integrative approach, considering the current limitations in hair treatment products.

Microneedling is a safe and effective way to improve various skin conditions with minimal side effects.

Minoxidil prevents serotonin loss from MDMA by affecting potassium channels and increasing Akt phosphorylation.

Foreskin keratinocytes and SVK14 cells express certain cytochrome P450 enzymes, unlike hair follicle keratinocytes.

Lepidium sativum seed extracts helped reduce inflammation and improve insulin response in obese rats on a high-fat diet.

Fat tissue extract may help treat vitiligo by reducing cell stress and promoting skin repair.

Inhibiting PLA2 enzymes may help treat inflammatory skin diseases like psoriasis and dermatitis.

Daily low-dose aspirin lowers minoxidil's effectiveness for hair loss treatment.

Caspases are enzymes important for both cell death and various non-lethal cell functions, affecting head development and hair growth, with different caspases playing specific roles.

Microneedling helps with hair loss, especially with 5% minoxidil, but more high-quality research is needed.