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    Research 121–150 of 1000+

    1. Synthesis, Characterization and Evaluation of 5α, 6β-Dihalo Androsterone Derivatives as 5α-Reductase Inhibitors Current Enzyme Inhibition · 2022
    2. 124 The Persistent Effects of 5α-reductase Inhibitors Used in the Treatment of Androgenic Alopecia on Men’s Health The Journal of Sexual Medicine · 2020
    3. 5α-Reductase Inhibitors in the Treatment of Androgenetic Alopecia International Journal of Cosmetic Surgery and Aesthetic Dermatology · 2001
    4. 5α-Reductase inhibitors in androgenetic alopecia Current Opinion in Endocrinology, Diabetes and Obesity · 2015
    5. Aromatase-independent testosterone conversion into estrogenic steroids is inhibited by a 5α-reductase inhibitor The Journal of Steroid Biochemistry and Molecular Biology · 2005 · 44 citations
    6. Overexpression of aldo-keto reductase 1C3 (AKR1C3) in LNCaP cells diverts androgen metabolism towards testosterone resulting in resistance to the 5α-reductase inhibitor finasteride The Journal of Steroid Biochemistry and Molecular Biology · 2012 · 45 citations
    7. Effect of the 5α-reductase enzyme inhibitor dutasteride in the brain of intact and parkinsonian mice 2017 · 16 citations
    8. Effect of Testosterone Supplementation With and Without a Dual 5α-Reductase Inhibitor on Fat-Free Mass in Men With Suppressed Testosterone Production JAMA · 2012 · 124 citations
    9. Comparison of finasteride (proscar®), a 5α reductase inhibitor, and various commercial plant extracts in in vitro and in vivo 5α reductase inhibition The Prostate · 1993 · 124 citations
    10. External genitalia abnormalities in male rats exposed in utero to finasteride, a 5α-reductase inhibitor Teratology · 1990 · 122 citations
    11. Critical Developmental Periods for Effects on Male Rat Genitalia Induced by Finasteride, a 5α-Reductase Inhibitor Toxicology and Applied Pharmacology · 1993 · 86 citations
    12. Outcome of long-term treatment with the 5α-reductase inhibitor finasteride in idiopathic hirsutism: clinical and hormonal effects during a 1-year course of therapy and 1-year follow-up Fertility and Sterility · 1996 · 75 citations
    13. Clinical and endocrine effects of finasteride, a 5α-reductase inhibitor, in women with idiopathic hirsutism Fertility and Sterility · 1995 · 70 citations
    14. Studies on Neurosteroids XXV. Influence of a 5.ALPHA.-Reductase Inhibitor, Finasteride, on Rat Brain Neurosteroid Levels and Metabolism Biological & Pharmaceutical Bulletin · 2008 · 61 citations
    15. Effects of the 5α-Reductase Inhibitor Finasteride on Serum Levels of Gonadal, Adrenal, and Hypophyseal Hormones and its Clinical Significance: A Prospective Clinical Study Steroids · 1998 · 56 citations
    16. Doping-Control Analysis of the 5α-Reductase Inhibitor Finasteride: Determination of Its Influence on Urinary Steroid Profiles and Detection of Its Major Urinary Metabolite Therapeutic Drug Monitoring · 2007 · 39 citations
    17. Decreased fertility in male rats administered the 5α-reductase inhibitor, finasteride, is due to deficits in copulatory plug formation Reproductive Toxicology · 1991 · 37 citations
    18. Long-term Oral Administration of 5α-reductase Inhibitor Attenuates Erectile Function by Inhibiting Autophagy and Promoting Apoptosis of Smooth Muscle Cells in Corpus Cavernosum of Aged Rats Urology · 2013 · 34 citations
    19. <i>Curcuma aeruginosa</i>, a novel botanically derived 5α-reductase inhibitor in the treatment of male-pattern baldness: a multicenter, randomized, double-blind, placebo-controlled study Journal of Dermatological Treatment · 2011 · 34 citations
    20. Reversible decreases of fertility in male Sprague-Dawley rats treated orally with finasteride, a 5α-reductase inhibitor Reproductive Toxicology · 1991 · 28 citations
    21. The 5α-reductase inhibitor Dutasteride but not Finasteride protects dopamine neurons in the MPTP mouse model of Parkinson’s disease Neuropharmacology · 2015 · 27 citations
    22. Progesterone-induced stimulation of mammary tumorigenesis is due to the progesterone metabolite, 5α-dihydroprogesterone (5αP) and can be suppressed by the 5α-reductase inhibitor, finasteride The Journal of Steroid Biochemistry and Molecular Biology · 2015 · 21 citations
    23. Discovery of a novel hybrid from finasteride and epristeride as 5α-reductase inhibitor Bioorganic & Medicinal Chemistry Letters · 2010 · 18 citations
    24. Finasteride, a 5α-reductase inhibitor, potentiates antinociceptive effects of morphine, prevents the development of morphine tolerance and attenuates abstinence behavior in the rat Hormones and Behavior · 2007 · 15 citations
    25. In Vivo Investigation in Pigs of Intestinal Absorption, Hepatobiliary Disposition, and Metabolism of the 5α-Reductase Inhibitor Finasteride and the Effects of Coadministered Ketoconazole Drug Metabolism and Disposition · 2011 · 14 citations
    26. A rapid method for obtaining finasteride, a 5α-reductase inhibitor, from commercial tablets Brain Research Protocols · 2002 · 14 citations
    27. Synthesis and Pharmacological Evaluation of New Progesterone Esters as 5.ALPHA.-Reductase Inhibitors Chemical and Pharmaceutical Bulletin · 2005 · 13 citations
    28. The 5α-reductase inhibitor finasteride increases suicide-related aggressive behaviors and blocks clozapine-induced beneficial effects in an animal model of schizophrenia Physiology & Behavior · 2018 · 12 citations
    29. COMBINATION OF AN ANTIANDROGEN AND A 5α-REDUCTASE INHIBITOR: A FURTHER STEP TOWARDS TOTAL ANDROGEN BLOCKADE? Endocrinology · 1991 · 9 citations
    30. The 5α-reductase inhibitor finasteride reduces opioid self-administration in animal models of opioid use disorder Journal of Clinical Investigation · 2021 · 8 citations