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This study found that overexpression of the mineralocorticoid receptor in a mouse model led to premature epidermal barrier development, keratinocyte apoptosis, and postnatal alopecia, indicating new roles for MR signaling in skin physiology.

In this study, researchers found that electrospun membranes with aligned surface topography advanced the immune response towards an adaptive stage and highlighted the role of T cells in hair follicle regeneration in mice, showcasing the intricate interactions between immune and skin cells.

This study found that quiescence in hair follicle stem cells acts as a tumor suppression mechanism for cutaneous squamous cell carcinoma, with Pten activity necessary to maintain this state.

This study reports that overexpressing the BMP antagonist noggin in mice inhibits eyelid opening by reducing apoptosis and delaying cell differentiation in the eyelid epithelium.

This study found that men receiving enzalutamide and other androgen-deprivation therapies may be at increased risk for QT prolongation and torsades de pointes.

This study found that Notch-related genes, including Notch1 and Notch2, and their ligands and regulators, have distinct patterns of expression during mouse hair vibrissa follicle development and the adult hair cycle.

This study found that IMT-P8, a novel cell-penetrating peptide, effectively facilitated the dermal delivery of proteins and peptides in mouse skin and cell lines, suggesting potential for topical applications in cosmetics and skin diseases.

This study found that amplifying Wnt signaling, either genetically or through topical application of liposomal Wnt3a, improved skin wound healing in a mouse model.

The researchers reported that during early embryogenesis and larval development in Silurana tropicalis, inhibiting steroidogenic enzymes cyp19 and srd5beta affects genes related to thyroid and reproductive systems.

This study suggests that a position effect disrupting TRPS1 expression may be linked to hypertrichosis in both Ambras syndrome in humans and a similar phenotype in Koa mice.

This study found that high-dose oral zinc significantly influences hair growth in mice, showing both inhibition and promotion effects depending on the timing and duration of administration.

In this study, a silk-inspired hydrogel system was developed that combines photodynamic therapy and wound healing, which may significantly reduce melanoma recurrence and enhance healing of infected wounds.

This study demonstrated that EdnrB signaling promotes melanocyte stem cell proliferation and differentiation, enhancing hair and epidermal melanocyte regeneration, especially under conditions of active Wnt signaling.

This study identified novel genetic associations with skin phenotypes such as age-spots, freckles, and hair characteristics in Japanese women, providing insights into the genetic basis of these traits.

This study found that activating Nrf2 in human hair follicles significantly reduced oxidative stress, lipid peroxidation, and protected against hair growth inhibition, suggesting a protective role for Nrf2 against redox insult in this context.

In this study, researchers created a core-shell nanozyme, CeO2@ZIF-8/Au, which autonomously regulates ROS levels to efficiently eliminate bacteria, reduce inflammation, and promote wound healing by balancing ROS generation and scavenging in response to environmental conditions.

In this study, enteroendocrine cells were shown to coordinate intestinal stem cell migration towards a wound in Drosophila by releasing a ligand that activates non-canonical Wnt signaling, aiding efficient tissue repair.

Hair can regrow after certain stem cells are lost because other stem cells can take over their role.

This study found that H-Ras activation in aged mouse skin leads to increased dysplasia and progression to in situ squamous cell carcinoma, highlighting an age-linked connection between immune changes, senescence, and cancer risk.

This study found that midazolam improved PTSD-associated behavioral deficits in rats through its action on the TSPO, CBR, and neurosteroidogenesis pathways.

In this study, mouse sweat gland development relied on a regulatory sequence initiated by Wnt/β-catenin signaling, and disruptions in Wnt, Eda, or Shh pathways led to distinct developmental failures.

In this study, researchers developed a method to control the valence states of Mo in nanozymes, optimizing their activity for ROS-related therapies, particularly acute kidney injury treatment, and enabling real-time monitoring with photoacoustic imaging.

In this review, the researchers detailed how the p63 transcription factor influences epithelial stem cell activities such as self-renewal, differentiation, and proliferation, highlighting the role of TAp63 and ΔNp63 isoforms in both normal tissue development and cancer pathogenesis.

In this study, miR-218-5p was found to enhance hair shaft growth and positively regulate the Wnt signaling pathway by targeting SFRP2 during skin and hair follicle development.

In this study, researchers observed that hyperandrogenic PCOS patients exhibited distinct miRNA and TGFβ signaling gene expression patterns in granulosa cells, suggesting these factors may play a role in PCOS pathogenesis.

This study observed that autologous PRP and PDRN injections improved hair thickness and density in women with pattern hair loss, with combined therapy showing greater improvement in thickness than PDRN alone.

This study found that skin microbiota, particularly in wild-type mice, promotes wound-induced hair follicle neogenesis and wound healing, highlighting the potential downsides of routine antibiotic use on skin regeneration.

This study found that oxidative damage is present in the mitochondria of PolG mice, which exhibit premature aging-like phenotypes due to mitochondrial dysfunction.

This study found that impaired autophagy plays a role in sonic hedgehog pathway-induced endometrial fibrosis, suggesting it as a potential target for treating intrauterine adhesion.

This study found that the microRNA miR-22 is a key regulator of the hair cycle, influencing hair loss by promoting the transition from growth to rest phases and repressing keratinocyte differentiation.