February 2022 in “Programa de Iniciação Científica - PIC/UniCEUB” This study compared the effectiveness of platelet-rich plasma and 5% topical minoxidil for androgenetic alopecia in men but did not report conclusive clinical results, relying on patient self-assessments.
October 2022 in “Skin appendage disorders” This study found that isolated scalp microneedling did not improve scalp coverage or hair density in male pattern hair loss patients, with no adverse events reported.
159 citations
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July 2014 in “Molecular pharmaceutics” This study found that MPEG-dihexPLA micelles significantly improved the skin deposition of tacrolimus compared to a marketed ointment, suggesting better targeted delivery with reduced systemic absorption.
138 citations
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August 1985 in “Journal of The American Academy of Dermatology” Minoxidil promotes hair growth in male pattern baldness.
79 citations
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January 1975 in “Food and Cosmetics Toxicology” In this study, oxidation hair dye formulations tested on mice showed no evidence of causing systemic toxicity or cancer over an 18-month period.
62 citations
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March 2015 in “PLOS ONE” In this study, microporous electrospun scaffolds pre-seeded with dermal fibroblasts accelerated wound healing and improved dermal matrix structure and hair follicle regeneration compared to acellular scaffolds in a rat model.
55 citations
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June 1987 in “PubMed” In this study, cyclosporin A treatment significantly increased hair length in nude mice compared to controls, but hair growth reversed after treatment stopped.
44 citations
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January 1997 in “British Journal of Dermatology” In this study, five women with androgenetic alopecia experienced severe facial and limb hypertrichosis after using 5% topical minoxidil, which resolved after discontinuing the treatment.
41 citations
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January 2012 in “Journal of Korean Medical Science” This study found a high prevalence of skin diseases, such as acne and tinea pedis, among Korean military personnel, highlighting their potential impact on soldiers' daily lives.
29 citations
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February 2011 in “PloS one” This study found that blocking corticotropin-releasing factor receptors with astressin-B promoted hair regrowth and prevented alopecia in a mouse model of stress-induced hair loss.
28 citations
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March 1987 in “Journal of The American Academy of Dermatology” This study observed that two out of twelve patients showed hair growth without the usual shedding after hair transplant surgery when treated with topical minoxidil, suggesting its potential as an adjunctive therapy during recovery.
27 citations
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March 2022 in “Forensic Toxicology” This review discusses micro-segmental hair analysis for forensic toxicology, emphasizing its potential to provide detailed drug distribution profiles and its application in investigations, while noting the method's limitations and future perspectives.
20 citations
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August 2017 in “Drug testing and analysis” This study used micro-segmental hair analysis to identify the day of drug intake and suggested differing uptake mechanisms for co-administered drugs based on their properties.
20 citations
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January 2017 in “Experimental Dermatology” In this study, deleting the Igf1 receptor in specific skin cells of mice affected hair follicle cycling but not overall skin health, suggesting Igf1r's role in hair cycle regulation through Bmp-4 activation.
19 citations
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September 2021 in “British journal of dermatology/British journal of dermatology, Supplement” This study suggests that pretreatment with a PPAR-γ modulator may prevent damage to hair follicle stem cells caused by a chemotherapy metabolite, potentially offering a strategy to mitigate permanent chemotherapy-induced alopecia.
13 citations
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May 1987 in “PubMed” This review explores the mechanisms and clinical trials of topical minoxidil for hair loss but presents no new clinical findings, emphasizing the need for better understanding of hair loss etiology for effective treatments.
11 citations
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January 2019 in “International Journal of Trichology” This study observed no significant improvement of mesotherapy over 5% topical minoxidil for male androgenic alopecia, despite a small increase in hair shaft diameter variation with mesotherapy.
9 citations
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February 2011 in “Revista Brasileira de Farmacognosia” This study reported that phytochemicals SA-4 and SA-6 from Tridax procumbens exhibited a dose-related immunostimulatory effect on mice, suggesting their potential as immunostimulators.
8 citations
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April 2020 in “Journal of The American Academy of Dermatology” This report describes nine women who were allergic to topical minoxidil but successfully tolerated low-dose oral minoxidil without significant adverse effects, suggesting it may be a viable alternative for those with similar allergies.
8 citations
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April 2017 in “International Journal of Dermatology” This study found that applying 5% topical minoxidil twice daily significantly increased nail growth rate in healthy participants compared to untreated nails, with effects observable from the first week.
8 citations
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October 2012 in “Transgenic Research” This study found that transgenic mice overexpressing human H-ferritin showed mild growth retardation and a temporary hairless phenotype, highlighting H-ferritin's physiological roles.
7 citations
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July 2021 in “JAAD case reports” This review discusses the potential of dupilumab for treating alopecia areata, reporting mixed outcomes with both improvement and new-onset hair loss observed in case reports.
7 citations
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January 2018 in “Materials Today: Proceedings” This study found that reinforcing epoxy with short human hair fibers and glass micro-spheres improved its wear resistance, suggesting potential applications in products like brake shoes and pads.
7 citations
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March 2013 in “Tetrahedron Letters” This study reports a new one-pot method for synthesizing chromeno-pyrimidine-N-oxides with high yield from 4-chloro-3-formylcoumarin and aromatic carboximide oximes, confirmed by X-ray analysis.
7 citations
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June 2012 in “Journal of dairy science” This study found that topical application of bovine milk polar lipids accelerated hair cycle progression in mice, showing potential for use in cosmetic products.
5 citations
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April 2021 in “Frontiers in Pharmacology” In this mouse study, the combination of minoxidil-coated lysozyme microbubbles and ultrasound significantly enhanced hair growth compared to minoxidil alone.
5 citations
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March 2016 in “Acute medicine & surgery” This case report describes a man who ingested a large amount of topical minoxidil solution and experienced serious and prolonged cardiovascular effects despite rapidly decreasing serum concentration levels.
5 citations
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March 2009 in “Pediatric Dermatology” The study found that pili bifurcati causes hair to intermittently split into two branches, each with its own outer layer.
5 citations
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January 1991 in “Acta Dermato Venereologica” This study found that topical CyA led to hair growth on human scalp skin grafts in nude mice, supporting its potential benefits for hair growth.
4 citations
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January 1989 This study suggests that applying topical minoxidil may improve hair graft survival after hair transplantation by reducing post-operative shedding.