Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This review discusses potential roles of zinc and copper in hair loss conditions like AA and TE, hypothesizing zinc's key role but noting that copper's effects need further investigation; it reports no new clinical findings.

This article reviews the book "Hair Loss: Principles of Diagnosis and Management of Alopecia" and reports no new research findings.

This study found that 4-MA is a potent inhibitor of testosterone 5α-reductase in human tissues, promising potential for treating androgen-dependent skin conditions like male pattern baldness.

In laboratory experiments, this study found that the topical prodrug SCD-153, a derivative of 4-methyl itaconate, reduced inflammation-related gene expression and induced significant hair growth in mice, suggesting it as a promising treatment candidate for alopecia areata.

This study found that 4-aminopyridine significantly enhanced skin wound healing by accelerating wound closure, improving skin architecture, and promoting hair follicle neogenesis and tissue regeneration.

This review discusses the impact of air pollution on skin health and suggests that targeting oxidative stress products like HNE could be a new strategy for treating related skin conditions.

This study found that phenyl-imidazole sulfonamide derivatives, particularly ISCK03, inhibited c-kit signaling and promoted depigmentation in various experimental settings, suggesting potential use as skin-whitening agents.

This study examined 4-azasteroids using 13C-NMR spectroscopy, detailing the NMR spectrum assignments and reporting a new molecular complex of finasteride with dioxane.

This article describes an organized diagnostic approach for identifying nonscarring and scarring alopecias to aid family physicians in making accurate in-office diagnoses, but it reports no new clinical findings.

This review suggests that platelet-rich plasma therapy shows promise for androgenetic alopecia and may be effective for some alopecia areata and cicatricial alopecia cases, but more robust trials are needed.

The researchers reported that a 4-aminopyridine-loaded gel promoted wound healing and hair follicle regeneration in burn models, suggesting it might be a promising alternative to existing burn treatments.

Reactive lipids from aging cells change the extracellular matrix, affecting cell function and inflammation.

This review summarizes recent advances in Treg cell biology, focusing on Foxp3's role in immune regulation and therapeutic reprogramming for immune dysregulatory disorders, but reports no new clinical results.

This study reported that women with polycystic ovary syndrome had higher glypican-4 levels compared to controls, indicating its significant role in hormonal regulation associated with the condition.

In this study, researchers observed that testicular 17β-hydroxysteroid dehydrogenase deficiency in an inbred Arab population in Israel leads to genital ambiguity at birth and progressive virilization after puberty.

This study identified a large deletion in the desmoglein 4 gene as the genetic basis of the Iffa Credo "hairless" rat's skin phenotype, linking it to lanceolate hair mutations.

In this study, researchers identified three molecules in hair that varied with age, suggesting potential markers for aging and targets for cosmetic products.

This study found that acellular dermal matrix scaffolds may facilitate full-thickness skin wound healing by promoting a pro-regenerative immune response through M2 macrophage polarization via the Lamtor1 pathway.

In this study, the researchers developed a cellulose nanofiber-based scaffold containing sitagliptin and zinc sulfide nanoparticles, which promoted scarless healing and hair follicle regeneration in rats by targeting DPP4+ fibroblasts, suggesting a novel approach for improved wound healing and skin regeneration.

This study found that the cytochrome P450 enzyme CYP-sb21 can hydroxylate cyclosporine A at multiple positions, reducing its immunosuppressive effects but retaining its hair growth-promoting side-effect, and suggests modifications to improve regioselectivity for commercial use.

This article discusses alopecia and the impact of hair loss on mental health, but it presents no new research findings and highlights the need for further studies.

The study found that growing dermal papilla cells in 3D spheroids enhances their activity with hair growth-promoting agents, such as minoxidil and TCQA, compared to traditional 2D cultures.

This study identified genetic variations in the DSG4 gene among sheep, revealing valuable markers for assessing their impact on wool traits.

This study found that while rat models treated with letrozole and dihydrotestosterone exhibit altered sterol, leukotriene, and steroid hormone profiles similar to human PCOS, significant differences remain.

This study explores the role of antidiabetic medications, particularly metformin, GLP-1 receptor agonists, and DPP-4 inhibitors, in managing PCOS, highlighting their combination with hormonal therapies and lifestyle interventions for a comprehensive treatment approach.

This study used infrared spectral imaging to show for the first time the distribution of glypican-4 and glypican-6 in hair follicles across different growth phases, highlighting the potential of this technique for studying alopecia.

This study examined lipid changes in rat models of polycystic ovarian syndrome, finding that letrozole and dihydrotestosterone treatments led to some lipid alterations similar to human PCOS, while other changes were unique to the models.

This article reviews the cutaneous side effects of immune checkpoint inhibitors and targeted therapies for skin cancers, noting that while generally mild, these effects can influence treatment decisions and quality of life, underscoring the need for physicians to be aware of these adverse reactions.

This study suggests that the hair growth-promoting effects of 4-O-methylhonokiol may be linked to its ability to modulate TGF-β-induced cell cycle arrest and oxidative stress in HaCaT cells.

In this study, acne severity in females was strongly associated with inflammatory lesion count and moderately associated with androgens, especially DELTA 4 and DHEAS promoting acne and SHBG reducing it.