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The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

Male hormones, or androgens, affect women's health in areas like mood and bone density, and hormone replacement therapy using antiandrogenic progestogens can improve mood disorders and alertness in menopausal women.

Hair loss in women can be slowed with treatment, but more research needed for better solutions.

Testosterone reduces heart damage and inflammation after injury.

Fulvestrant is a well-tolerated new treatment for advanced breast cancer that may delay chemotherapy.

Hormonal interactions, especially involving DHT and estrogen, play a key role in BPH development and treatment.

Adolescents with PCOS have higher levels of certain androgens, which are linked to hair growth but don't help diagnose PCOS better than testosterone levels.

Girls with PCOS have higher levels of certain androgens, which are linked to excess hair growth, but these androgens don't help diagnose PCOS.

The N363S gene variant does not cause higher adrenal androgen levels in women with polycystic ovary syndrome.

Diagnosing hyperandrogenism in women is complex and requires accurate testing methods and consideration of SHBG levels.

Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.

Finasteride lowers DHT levels and raises testosterone in a dose-dependent way.

Finasteride may treat baldness but less effective for those with 5α-reductase deficiency.

The method can measure multiple steroids in human hair to study long-term steroid metabolism, especially in newborns and children.

Changes in gut bacteria can contribute to the development of Polycystic Ovary Syndrome (PCOS), affecting metabolism, immunity, and causing inflammation. Treatments may involve adjusting these factors.

Most women referred for excess male hormone symptoms had polycystic ovary syndrome (PCOS), with other conditions being less common.

Women's ovarian hormones and adrenal androgens change throughout life, affecting hair loss and health.

Mice without the enzyme HSD17B3 still produce normal testosterone, suggesting they have different ways to make it compared to humans.

Some women with PCOS have CYP21 mutations and IRS1 variants, but these genetic factors are not major contributors to PCOS.

Olfactory receptors found outside the nose may offer new treatments for diseases like cancer and help in wound healing and hair growth.

Diagnosing PCOS is challenging due to its complex and varied symptoms.

Bolandiol, a synthetic steroid, builds muscle and bone without greatly affecting sex glands, and works differently from other hormones.

Men's sensitivity to male hormones might affect how severe COVID-19 gets for them.

Women with effluvium have higher levels of certain urinary steroids, possibly due to stress and increased adrenal activity.

The document concludes that early and personalized treatment for PCOS in adolescents is crucial to manage symptoms and prevent long-term health issues.

About 7% to 15% of Iranian women have polycystic ovary syndrome, depending on the criteria used to diagnose it.

Indigofera tinctoria leaf extract has many compounds that support its traditional medicinal uses.

Diet and supplements can significantly affect acne, with some foods and nutrients reducing and others worsening it.

About 13% of women had idiopathic hirsutism and 8.5% had polycystic ovary syndrome in a group of Iranian women.

DHEA improved brain function and behavior in old monkeys and had additional health benefits.