research Stem Cells, Organoids and Their Applications for Human Diseases: Special Issue of BMB Reports in 2023
Organoids created from stem cells are used to model diseases, test drugs, and develop personalized and regenerative medicine.
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research Green Regenerative Hydrogel Wound Dressing Functionalized by Natural Drug-Food Homologous Small Molecule Self-Assembled Nanospheres
The new hydrogel dressing with natural molecules helps heal wounds faster and improves skin repair.
research Eccrine Sweat Glands Associate With the Human Hair Follicle Within a Defined Compartment of Dermal White Adipose Tissue
Sweat glands and hair follicles are structurally connected within a specific layer of skin fat.
research Charting the Bromodomain BRD4: Towards the Identification of Novel Inhibitors with Molecular Similarity and Receptor Mapping
Researchers identified promising inhibitors for the BRD4 protein, including finasteride and amentoflavone.
research TGFβ Family Mimetic Peptide Promotes Proliferation of Human Hair Follicle Dermal Papilla Cells and Hair Growth in C57BL/6 Mice
A peptide called DPS-1 helps human scalp cells grow and stimulates hair growth in mice.
research Organ Regeneration: Comprehensive Overview of Organogenesis and Next-Generation Regenerative Therapy
The book explains how to grow and repair organs using new lab techniques.
research Spatial Gene Profiling in the Ischemic Heart
A new technology showed that the SOX9 gene might control heart scar formation after injury, suggesting new treatment possibilities.
research Design, Synthesis and Anti-Tumor Evaluation of Novel Thiohydantoin Congeners as Androgen Receptor Antagonists With In Vivo Study
A new compound, 3a, effectively fights prostate cancer better than finasteride.
research A Texture-Driven Model for Male Baldness
The document concludes that the new model realistically simulates male baldness and could be useful for medical purposes and entertainment.
research 254 Withdrawn
Aging causes sweat glands to shrink, leading to skin issues, and blue light can help hair grow.
research Androgenetic Alopecia: New Insights into the Pathogenesis and Mechanism of Hair Loss
The arrector pili muscle plays a key role in hair loss in androgenetic alopecia.
research Telocytes in Human Skin – Are They Involved in Skin Regeneration?
Telocytes might help with skin repair and regeneration.
research FOXN1: A Master Regulator Gene of Thymic Epithelial Development Program
The FOXN1 gene is crucial for developing immune cells and preventing immune disorders.
research Epidermal Stem Cells Manipulated by pDNA-VEGF165/CYD-PEI Nanoparticles Loaded Gelatin/β-TCP Matrix as a Therapeutic Agent and Gene Delivery Vehicle for Wound Healing
The gelatin/β-TCP scaffold with nanoparticles improves wound healing and skin regeneration.
research Androgenetic Alopecia: New Insights Into the Pathogenesis and Mechanism of Hair Loss
New model shows muscle affects hair loss differently in men and women.
research Developing Stratified Epithelia: Lessons from the Epidermis and Thymus
The skin and thymus develop similarly to protect and support immunity.
research Characterization of Human Dermal Papilla Cells in Alginate Spheres
Alginate spheres help maintain hair growth potential in human cells for hair loss treatment.
research Ginsenoside Re Prevents 3-Methyladenine-Induced Catagen Phase Acceleration by Regulating Wnt/Beta-Catenin Signaling in Human Dermal Papilla Cells
Ginsenoside Re from Panax ginseng may prevent hair loss by maintaining autophagy and Wnt signaling in hair cells.
research Integrin α3β1 in Hair Bulge Stem Cells Modulates CCN2 Expression and Promotes Skin Tumorigenesis
Removing integrin α3β1 from hair stem cells lowers skin tumor growth by affecting CCN2 protein levels.
research Injectable Gelatin/Metal/Tea Polyphenol Double Nanonetworks for Diabetic Wound Healing
New injectable hydrogels with gelatin, metal, and tea polyphenols help heal diabetic wounds faster by controlling infection, improving blood vessel growth, and managing oxidative stress.
research Melanocytes in Regenerative Medicine Applications and Disease Modeling
Melanocytes are important for normal body functions and have potential uses in regenerative medicine and disease treatment.
research Rand Protease: The Role of Calcium-Binding Site on Stability with Mutagenesis and The Effectiveness on Leather Dehairing
The enzyme Rand protease works well for leather dehairing and its stability is important, with Leu75 playing a key role.
research Cloning, Computational Analysis and Expression Profiling of Steroid 5 Alpha-Reductase 1 (SRD5A1) Gene During Reproductive Phases and Ovatide Stimulation in Endangered Catfish, Clarias Magur
The research identified and described a gene important for hormone conversion in endangered catfish, which varies in activity during different reproductive stages and after hormone treatment.
research Potential Application of PBM in Hair Follicle Organoid Culture for the Treatment of Androgenic Alopecia
Light therapy might help treat hereditary hair loss by improving hair follicle growth in lab cultures.
research Feature Identification of Skin Diseases and Laser Therapy with a Portable Optical Coherence Imaging System
A portable imaging system shows promise for diagnosing skin diseases and checking laser treatment effects.
research Prostacyclin Pathway to Enhance Wound Healing in Diabetic Foot Ulcers
Treprostinil, a drug, can delay wound healing in healthy cells but doesn't affect diabetic foot ulcer cells, suggesting further research could help understand its role in treating these ulcers.
research Case Report: Bi-Allelic Missense Variant in the Desmocollin 3 Gene Causes Hypotrichosis and Recurrent Skin Vesicles
A new genetic change in the DSC3 gene is linked to a rare condition causing hair loss and skin blisters in a child.
research Multi-View Light Sheet Fluorescence Microscopy for Imaging Cellular Self-Assembly in Spheroids of Human Hair Follicle Dermal Papilla Cells and Keratinocytes
The technique effectively shows how human skin and hair cells form into ball-like structures.
research Genetics of Hidradenitis Suppurativa
Hidradenitis Suppurativa has genetic links, with certain gene mutations more common in patients and a third of cases having a family history.
research The Distribution of Preputial Vessels at Different Severity of Rat Congenital Hypospadias Model
Micro-CT helps identify suitable areas for surgical procedures based on blood vessel distribution in hypospadias-affected rats.