Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This abstract introduces 3D bioprinted skin grafts as a promising alternative to traditional skin grafts, emphasizing how using stem cells in the bioink can enhance vascularization and hair follicle regeneration, potentially improving graft integration and function without the donor site risks.

This study used atomic force microscopy to identify significant morphological differences in hair from patients with lichen planopilaris compared to healthy controls, noting more scratches, uneven edges, and pitted scales in affected hair, which may aid future research on the condition.

In this study, researchers used atomic force microscopy to capture and analyze morphological changes in the surface of healthy hair, identifying features such as pitting and rod-shaped macro-fibrillar elements, which could inform future research on hair conditions and care.

3D-oxy exosomes may significantly boost hair growth, offering new treatment options for hair loss.

This study found that tight junctions extend to the most superficial layer of the stratum granulosum in human skin, challenging previous claims of their limited presence in the epidermis.

This study found that the desmosomal protein desmoplakin is crucial for proper epidermal morphogenesis and radial intercalation in developing Xenopus embryos, affecting keratin organization and ectodermal structures.

New drugs for Alzheimer's and rheumatoid arthritis advanced, a Zika vaccine is in development, and there were business deals in anesthesia and oncology.

This review covers current knowledge of tricoscopy's applications in diagnosing and monitoring scalp and hair disorders but presents no new clinical results.

This research found that keratin hydrogels derived from human hair may support cell viability and proliferation, indicating potential as 2D and 3D soft tissue culture scaffolds.

This review discusses the potential of adipose-derived stem cells for treating vitiligo, hair loss, and chronic wound healing, but reports no new clinical results and suggests the need for further investigation.

This study found that a conditioned medium from human umbilical cord mesenchymal stem cells cultured in a gelatin sponge significantly enhanced hair growth and promoted skin angiogenesis in a mouse model, more effectively than a monolayer culture.

This study found that male pattern baldness in European males is strongly heritable and associated with genetic markers linked to earlier puberty, bone density, and pancreatic function.

This review discusses strategies to enhance mesenchymal stem cell therapy effectiveness but reports no new clinical results; it highlights the need for improved consistency and efficacy in MSC-based treatments.

This review suggests that skin may largely protect itself from CYP-generated reactive metabolites due to higher conjugating enzyme activities, while highlighting limitations in modeling human skin metabolism experimentally.

This study reported the successful isolation of epithelial stem cells from mouse embryonic skin using a simple culture method, with the cells showing the potential to differentiate into multiple cell types.

In this study, CD109 overexpression in transgenic mice led to reduced inflammation and improved collagen organization during wound healing without affecting wound closure.

This study found that a titrated extract of Centella asiatica enhanced the hair growth potential of 3D spheroid cultured human dermal papilla cells.

In this study, knockdown of XIST in 3D-cultured dermal papilla cells inhibited hair follicle regeneration by interfering with miR-424 and hedgehog signaling, highlighting XIST's role in hair development.

This study isolated a bioactive peptide from Trapa japonica fruit and found that it may protect human dermal papilla cells from DHT-induced stress, suggesting potential for biomedical applications.

This study found that in a mouse model of Leigh syndrome, rapamycin alters brain proteome and may extend survival by targeting protein kinase C.

This study found that pelage abnormalities in Harlequin mutant mice are linked to severe AIF deficiency and associated with altered expression of genes related to hair structure.

This study explored the creation of 3D-printed baricitinib pills using polylactic acid and found that the doughnut-shaped tablets increased surface area and drug release, with 59% released from the higher concentration pill over 24 hours.

This review discusses the dynamic changes in chromatin organization and nuclear morphology during cellular processes like differentiation and disease, highlighting recent advances in understanding these epigenetic mechanisms without presenting new experimental findings.

This study concluded that a new model of reconstructed human epidermis using keratinocytes from plucked hair follicles offers a less-invasive alternative to conventional skin-derived models for skin research.

This study found that hair follicle stem cells in mice have an unexpected ability to adaptively determine their differentiation pathways, maintaining tissue architecture despite external stimuli.

This study demonstrated that hyaluronan gel is a promising biomaterial for 3-D in vitro culture of mouse ovarian follicles, supporting the production of fertilizable metaphase II oocytes.

This study found that deoxycholic acid effectively reduces excess fat under the chin, showing significant volume reduction and increased patient satisfaction in both aesthetic improvements and recovery experiences among the 13 participants.

In this study, 3D planned resection and reconstruction for skull defects after resection of cSCC with bony invasion led to accurate procedures, though patient-specific factors should guide treatment decisions.

In this study, researchers used a CRISPR-based method to correct mutations in the COL7A1 gene in stem cells from RDEB patients, restoring normal collagen expression in engineered skin grafts in mice.