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Too much Smad7 changes skin and hair development by breaking down a protein called β-catenin, leading to more oil glands and fewer hair follicles.

Aging causes skin stem cells to work less effectively.

Hyaluronate fragments can help reverse skin thinning by working with the CD44 receptor.

Adam10 enzyme is crucial for healthy skin and proper Notch signaling.

Human dermal fibroblasts are the main cells targeted by a virus that can cause a deadly skin cancer, and a certain inhibitor can effectively block this infection.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Skin-derived precursors in hair follicles come from different origins but function similarly.

Wharton’s Jelly stem cells from the umbilical cord improve skin healing and hair growth without scarring.

Skin fat helps with body temperature control and has other active roles in health.

Mutations in Gasdermin A3 cause skin inflammation and hair loss by disrupting mitochondria.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

The nude gene causes skin cell overgrowth and improper development, leading to hair and urinary issues.

Trichohyalin-like proteins are essential for the development of skin structures like hair, nails, and feathers.

Androgens cause skin issues like acne and hair growth in women, often due to PCOS, and can be treated with medication and lifestyle changes.

Human hair follicle cells can grow hair when put into mouse skin if they stay in contact with mouse cells.

Prolactin affects the production of different keratins in human hair, which could lead to new treatments for skin and hair disorders.

Fat from the body can help improve hair growth and scars when used in skin treatments.

Multiphoton microscopy is a promising tool for detailed skin imaging and could improve patient care if its challenges are addressed.

Nanocarrier-loaded gels improve drug delivery for cancer, skin conditions, and hair loss.

Healthy mitochondria in skin cells are essential for proper hair growth and skin cell interaction in mice.

Activating β-catenin in different skin stem cells causes various types of hair growth and skin tumors.

Skin tumor regression is helped by retinoic acid signaling blocking Wnt signaling.

BLIMP1 is essential for skin maintenance but not for defining sebaceous gland progenitors.

A new hydrogel with stem cells from human umbilical cords improves skin wound healing and reduces inflammation.

C/EBPalpha and C/EBPbeta are crucial for normal skin and oil gland cell development in adult mice.

Exosomes can improve skin health and offer new treatments for skin repair and rejuvenation.

The new dutasteride formula can be applied to the skin, may promote hair growth, and has fewer side effects.

The vitamin D receptor is essential for skin stem cells to grow, move, and become different cell types needed for skin healing.

CYLD mutations cause a variety of skin tumors with symptoms starting around age 16, and treatments are currently limited.

Disrupting Smad4 in mouse skin causes early hair follicle stem cell activity that leads to their eventual depletion.