research Topical Application of a Protein Kinase C Inhibitor Reduces Skin and Hair Pigmentation
Applying a specific inhibitor lightens skin and hair color.
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research Tissue Engineering of the Reproductive System
Cell transplantation faces challenges in genitourinary reconstruction, but alternative tissue sources and microencapsulation show promise.
research Hair Follicle Generation by Injections of Adult Human Follicular Epithelial and Dermal Papilla Cells into Nude Mice
Injecting a mix of human skin and hair cells into mice can grow new hair.
research Identification of Stem Cell Populations in Sweat Glands and Ducts Reveals Roles in Homeostasis and Wound Repair
The study found that sweat glands contain different types of stem cells that help with healing and maintaining healthy skin.
research Two Mechanisms Regulate Keratin K15 Expression in Keratinocytes: Role of PKC/AP-1 and FOXM1 Mediated Signaling
Keratin 15 expression in skin cells is regulated by two mechanisms involving PKC/AP-1 and FOXM1.
research Bioengineering Skin Constructs
Future research should focus on making bioengineered skin that completely restores all skin functions.
research Emerging Roles of Transit-Amplifying Cells in Tissue Regeneration and Cancer
Transit-amplifying cells are crucial for tissue repair and can contribute to cancer when they malfunction.
research T-Cell Reconstitution After Thymus Xenotransplantation Induces Hair Depigmentation and Loss
T-cell reconstitution after thymus transplantation can cause hair whitening and loss.
research Dermal Papilla Cells Induce Keratinocyte Tubulogenesis in Culture
Skin cells can help create early hair-like structures in lab cultures.
research Regenerative Potential and Clinical Application of Mesenchymal Stem Cell-Derived Exosomes
MSC-derived exosomes can help treat COVID-19, hair loss, skin aging, and arthritis.
research Wound Regeneration Deficit in Rats Correlates with Low Morphogenetic Potential and Distinct Transcriptome Profile of Epidermis
Rats can't grow new hair follicles after skin wounds, unlike mice, due to differences in gene expression and response to WNT signaling.
research Keratinocytes and Adipose-Derived Mesenchymal Stem Cells: The Heir and the Spare to Regenerative Cellular Therapies for Difficult-to-Heal Skin Wounds
Keratinocytes and adipose-derived stem cells can effectively heal difficult skin wounds.
research Fascia Layer - A Novel Target for the Application of Biomaterials in Skin Wound Healing
The fascial layer is a promising new target for wound healing treatments using biomaterials.
research Australasian Society for Dermatology Research Meeting, May 2006
The meeting highlighted the genetic basis of female pattern hair loss and various skin health insights.
research Identification of Drug-Specific Public TCR Driving Severe Cutaneous Adverse Reactions
Researchers found a specific immune receptor in patients that causes severe skin reactions to a drug.
research Involvement of Follicular Stem Cells in Forming Not Only the Follicle but Also the Epidermis
Hair follicle stem cells can form both hair follicles and skin.
research Human Epithelial Hair Follicle Stem Cells and Their Progeny: Current State of Knowledge, the Widening Gap in Translational Research and Future Challenges
We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.
research FOXN1 Deficiency: From the Discovery to Novel Therapeutic Approaches
New treatments for immune disorders caused by FOXN1 deficiency are promising.
research Comparison of Calcium and Barium Microcapsules as Scaffolds in the Development of Artificial Dermal Papillae
Calcium microcapsules are better for long-term use in artificial dermal papilla, while barium microcapsules are good for short-term.
research Characterization and Isolation of Stem Cell-Enriched Human Hair Follicle Bulge Cells
Researchers successfully isolated and identified key markers of stem cell-enriched human hair follicle bulge cells.
research Estimating the Contribution of the Prostate to Blood Dihydrotestosterone
The normal human prostate does not significantly affect blood DHT levels.
research Stem Cells from Human Hair Follicles: First Mechanical Isolation for Immediate Autologous Clinical Use in Androgenetic Alopecia and Hair Loss
Stem cells from hair follicles can safely treat hair loss.
research Generation of Trichogenic Adipose-Derived Stem Cells by Expression of Three Factors
Scientists made stem cells that can grow hair by adding three specific factors to them.
research TGF-β2 Is Specifically Expressed in Human Dermal Papilla Cells and Modulates Hair Folliculogenesis
TGF-β2 plays a key role in human hair growth and development.
research Neural, Adipocyte and Hepatic Differentiation Potential of Primary and Secondary Hair Folicle Stem Cells Isolated from Arbas Cashmere Goats
Hair follicle stem cells from Arbas Cashmere goats can become fat, nerve, and liver cells.
research Cultured Peribulbar Dermal Sheath Cells Can Induce Hair Follicle Development and Contribute to the Dermal Sheath and Dermal Papilla
Certain cells from hair follicles can create new hair and contribute to hair growth when implanted in mice.
research Genetic Ablation of the CDP/Cux Protein C Terminus Results in Hair Cycle Defects and Reduced Male Fertility
Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.
research Identification of Hair Shaft Progenitors That Create a Niche for Hair Pigmentation
Scientists found cells in hair that are key for growth and color.
research Wound Healing Impairment in Type 2 Diabetes Model of Leptin-Deficient Mice: A Mechanistic Systematic Review
Leptin-deficient mice, used as a model for Type 2 Diabetes, have delayed wound healing due to impaired contraction and other dysfunctional cellular responses.
research The Mesenchymal Niche of the Hair Follicle Induces Regeneration by Releasing Primed Progenitors from Inhibitory Effects of Quiescent Stem Cells
The study found that a specific area of the hair follicle helps start hair growth by reducing the blocking effects on certain cells and controlling growth signals.