research Modulation of Glucocorticoid Action and the Treatment of Type-2 Diabetes
Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.
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research Bacteria Induce Skin Regeneration via IL-1β Signaling
Skin bacteria, specifically Staphylococcus aureus, help in wound healing and hair growth by using IL-1β signaling. Using antibiotics on skin wounds can slow down this natural healing process.
research Heterozygous FOXN1 Variants Cause Low TRECs and Severe T Cell Lymphopenia, Revealing a Crucial Role of FOXN1 in Supporting Early Thymopoiesis
FOXN1 gene variants cause low T cells and immune issues from birth.
research Modulating Hair Follicle Size with Wnt10b/DKK1 During Hair Regeneration
Wnt10b makes hair follicles bigger, but DKK1 can reverse this effect.
research The Prostamide-Related Glaucoma Therapy, Bimatoprost, Offers a Novel Approach for Treating Scalp Alopecias
Bimatoprost, a glaucoma medication, may also help treat hair loss.
research Post-Transcriptional Regulation of Keratinocyte Progenitor Cell Expansion, Differentiation, and Hair Follicle Regression by miR-22
miR-22, a type of microRNA, controls hair growth and its overproduction can cause hair loss, while its absence can speed up hair growth.
research Ultrastructural Evaluation of the Radioprotective Effects of Melatonin Against X-Ray-Induced Skin Damage in Albino Rats
Melatonin may reduce skin damage caused by X-rays in rats.
research Hair-Cycle-Dependent Expression of Parathyroid Hormone-Related Protein and Its Type I Receptor: Evidence for Regulation at the Anagen to Catagen Transition
Parathyroid hormone-related protein helps control hair growth phases in mice.
research Spatiotemporal Control of CRISPR/Cas9 Gene Editing
The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.
research Novel Therapeutic Approaches in Utilizing Platelet Lysate in Regenerative Medicine: Are We Ready for Clinical Use?
Platelet lysate is a promising, cost-effective option for regenerative medicine with potential clinical applications.
research Steroidal 5α-Reductase and 17α-Hydroxylase/17,20-Lyase (CYP17) Inhibitors Useful in the Treatment of Prostatic Diseases
Certain drugs that block specific enzymes can help treat prostate diseases.
research Skin Wounds in the MRL/MPJ Mouse Heal with Scar
MRL/MpJ mice's skin wounds heal with scars, unlike their ear wounds which can regenerate.
research Design of a Biofluid-Absorbing Bioactive Sandwich-Structured Zn–Si Bioceramic Composite Wound Dressing for Hair Follicle Regeneration and Skin Burn Wound Healing
Wound dressing absorbs fluid, regenerates hair follicles, and heals skin burns.
research BLIMP1 Is Required for Postnatal Epidermal Homeostasis but Does Not Define a Sebaceous Gland Progenitor Under Steady-State Conditions
BLIMP1 is essential for skin maintenance but not for defining sebaceous gland progenitors.
research Novel Skin Patch Combining Human Fibroblast-Derived Matrix and Ciprofloxacin for Infected Wound Healing
The new skin patch with human matrix and antibiotic improves wound healing.
research Micro-Needling Depth Penetration, Presence of Pigment Particles, and Fluorescein-Stained Platelets: Clinical Usage for Aesthetic Concerns
Micro-needling effectively improves wrinkles, scars, and hair growth, but proper technique and safety are important.
research Enhanced Cutaneous Wound Healing by Functional Injectable Thermo-Sensitive Chitosan-Based Hydrogel Encapsulated Human Umbilical Cord-Mesenchymal Stem Cells
A new hydrogel with stem cells from human umbilical cords improves skin wound healing and reduces inflammation.
research Nanoparticles in Wound Healing: From Hope to Routine
Nanoparticles show promise for better wound healing, but more research is needed to ensure safety and effectiveness.
research Generation and Characterization of Rat Liver Stem Cell Lines and Their Engraftment in a Rat Model of Liver Failure
Researchers created rat liver stem cells that could help repair liver failure in rats and may be useful for studying human liver diseases.
research Cultured Human and Rat Tooth Papilla Cells Induce Hair Follicle Regeneration and Fiber Growth
Tooth papilla cells can help regenerate hair follicles and grow hair.
research Trichohyalin: Presence in the Granular Layer and Stratum Corneum of Normal Human Epidermis
Trichohyalin is also found in the outer layers of normal human skin.
research The Novel Mechanisms and Applications of Exosomes in Dermatology and Cutaneous Medical Aesthetics
Exosomes can improve skin health and offer new treatments for skin repair and rejuvenation.
research Common Causes of Hair Loss: Clinical Manifestations, Trichoscopy, and Therapy
The document concludes that understanding and treating hair loss requires recognizing its various types and using appropriate diagnostic tools and treatments.
research Improving Translational Research in Sex-Specific Effects of Comorbidities and Risk Factors in Ischemic Heart Disease and Cardioprotection: Position Paper and Recommendations of the ESC Working Group on Cellular Biology of the Heart
The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.
research Ultrasound-Activated Particles as CRISPR/Cas9 Delivery System for Androgenic Alopecia Therapy
Scientists have created a new hair loss treatment using ultrasound to deliver gene-editing particles, which resulted in up to 90% hair regrowth in mice.
research Novel TMEM173 Mutation and the Role of Disease-Modifying Alleles
A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.
research Noncoding dsRNA Induces Retinoic Acid Synthesis to Stimulate Hair Follicle Regeneration via TLR3
Noncoding dsRNA boosts hair growth by activating TLR3 and increasing retinoic acid.
research Preparation and Characterization of Dutasteride-Loaded Nanostructured Lipid Carriers Coated with Stearic Acid-Chitosan Oligomer for Topical Delivery
The new dutasteride formula can be applied to the skin, may promote hair growth, and has fewer side effects.
research Changing the Shape of Hair with Keratin Peptides
Keratin peptides can change hair shape gently without harsh chemicals.
research Androgens Modify Wnt Agonists/Antagonists Expression Balance in Dermal Papilla Cells Preventing Hair Follicle Stem Cell Differentiation in Androgenetic Alopecia
Androgens prevent hair growth by changing Wnt signals in cells.