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Advanced human skin models improve drug development and could replace animal testing.

New materials and methods could improve skin healing and reduce scarring.

New indole-based compounds, particularly cemtirestat, show promise as dual-function drugs for diabetic complications.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Platelet Rich Plasma (PRP) shows promise for tissue repair and immune response, but more research is needed to fully understand it and optimize its use.

Researchers created a potential skin substitute using a biodegradable mat that supports skin cell growth and layer formation.

Nanoparticles show promise for better wound healing, but more research is needed to ensure safety and effectiveness.

LED light therapy is effective for skin and hair treatments but requires careful use to minimize risks.

Chemicals and stem cells combined have advanced regenerative medicine with few safety concerns, focusing on improving techniques and treatment effectiveness.

Chitin and chitosan are useful in cosmetics for oral care, haircare, and skincare, including UV protection and strength improvement.

Too much Smad7 changes skin and hair development by breaking down a protein called β-catenin, leading to more oil glands and fewer hair follicles.

Hair restoration surgery effectively treats hair loss with natural-looking results, using techniques like stem cells and platelet-rich plasma.

Fully regenerating human hair follicles not yet achieved.

Safflower extract helps protect hair follicle cells from damage caused by chemotherapy.

The conclusion is that the nuclear lamina and LINC complex in skin cells respond to mechanical signals, affecting gene expression and cell differentiation, which is important for skin health and can impact skin diseases.

Nanomaterials can significantly improve wound healing and future treatments may include smart, real-time monitoring.

CRH in the skin acts like the body's stress response system, affecting cell behavior and immune activity.

Hard skin features like scales, feathers, and hair evolved through specific protein changes in different animal groups.

Notch signaling disruptions can cause various skin diseases.

Leptin-deficient mice, used as a model for Type 2 Diabetes, have delayed wound healing due to impaired contraction and other dysfunctional cellular responses.

Some therapies using stem cells and platelet-rich plasma may help treat osteoarthritis, but more research is needed to ensure they are safe and effective.

Tiny fat-derived particles can help repair soft tissues by changing immune cell types.

PRP helps skin heal, possibly through special cells called telocytes.

Mesenchymal stem cells could help treat aging-related diseases better than current methods.

Human umbilical cord stem cell vesicles may help treat aging and related diseases.

Autologous platelet concentrates show promise in esthetic treatments but need more standardized research.

Antiviral drugs, especially daclatasvir, may be a new treatment for a rare skin disease, improving survival and reducing symptoms in mice.

New regenerative medicine-based therapies for hair loss look promising but need more clinical validation.

Cinnamaldehyde helps bone healing initially but may slow healing later unless combined with DHT treatment.

The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.