10 citations
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February 2014 in “Fitoterapia” This study found that Pomiferin may effectively stimulate extracellular matrix protein expression in skin and scalp models, with results comparable to retinol, suggesting potential as a topical treatment ingredient.
6 citations
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March 2021 in “International Journal of Pharmaceutics” This study reported that a subcutaneous injection formulation using PLGA microspheres to release finasteride stably achieved sustained monthly drug delivery without burst release in beagle dogs, with a dose of 16.8 mg identified as optimal for potential first-in-human trials.
4 citations
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March 2023 in “Journal of controlled release” This study reports that a novel bioabsorbable nano-micelle hybridized hydrogel scaffold may reduce postoperative melanoma recurrence and mitigate the side effects of doxorubicin in mouse models.
2 citations
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December 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, overexpression of miR-29 in mice led to aging-related phenotypes and early lethality, demonstrating its significant role in driving aging processes.
1 citations
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April 2023 in “Scientific Reports” This study reported that newly developed RADA16-I peptide hybrids, with active motifs like GHK and KGHK, demonstrated improved wound healing in a mouse skin injury model without cytotoxicity, suggesting they might be effective scaffolds for tissue engineering and regeneration.
1 citations
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September 2022 in “Journal of dermatological science” This study found that a combination of vitamins in hair care products promoted hair shaft elongation in a mouse model by activating the PlGF/VEGFR-1 signaling pathway.
1 citations
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February 2021 in “Journal of Natural Remedies” This study found that a combination of Ficus religiosa and Morus alba extracts promoted hair growth and Hair Follicle regeneration in a mouse model of hair loss by inducing the anagen phase and upregulating stem cell-associated genes.
April 2026 in “Scientific Reports” In this study, the proposed MSF-VMDNet, combining dual encoder networks with a multi-frequency domain mechanism, significantly outperformed existing methods in segmenting skin cancer tissues from histological slide images, achieving high accuracy with an MIoU of 95.37% and a Dice coefficient of 95.11%.
June 2025 in “Current Issues in Molecular Biology” In this study, researchers using a UVB-induced mouse model identified the gene COL7A1 as a novel marker for hair luster, finding that minoxidil, caffeine, and biotin effectively restored its expression, indicating potential therapeutic strategies.
April 2025 in “Drug Design Development and Therapy” This study observed that the herbal extract WJWE promoted hair growth and protected hair follicle cells in a DHT-induced murine model of androgenetic alopecia, potentially by engaging the SIRT1/JNK/p38 MAPK and Wnt5A/β-Catenin signaling pathways.
September 2024 in “Stem Cell Research & Therapy” This study found that extracellular vesicles derived from hyaluronic acid-stimulated induced pluripotent stem cells significantly improved hair growth in a model of androgenetic alopecia in mice by enhancing Wnt/β-catenin signaling and regulating androgen receptor activity, showing comparable results to the commonly used treatment finasteride.
August 2024 in “Life Science Alliance” This study found that topical application of TGF-β mimic promoted enhanced wound healing and tissue regeneration in mice, suggesting its potential as a therapeutic option for improving wound healing.
March 2024 in “Advanced science” This study observed that a novel extracellular matrix hydrogel made from human fibroblast-derived matrix improved wound healing in animal models, showing significant effects such as hair follicle formation, reduced inflammation, enhanced pro-healing growth factor levels, and interaction with macrophages, compared to traditional collagen hydrogels.
March 2024 in “EMBO molecular medicine” This study found that the antiviral drug daclatasvir significantly improved fibrosis and quality of life in a mouse model of recessive dystrophic epidermolysis bullosa, suggesting potential for treating this and other fibrotic diseases.
January 2024 in “Biological Research” This study found that mesenchymal stem cell-derived exosomes reduced hearing and hair cell loss caused by neomycin in experimental models by modulating autophagy, which promoted cell survival and lowered oxidative stress and apoptosis, indicating potential for deafness treatment.
April 2023 in “Journal of Investigative Dermatology” This study found that inhibiting PI3 kinase in epidermal stem cells reduces YBX1 phosphorylation, thereby decreasing cellular senescence and enhancing wound healing and regeneration in adult-derived skin models.
January 2023 in “Theranostics” This study reported that a curcumin-zinc microneedle patch improved hair regrowth and wound healing in animal models, suggesting potential as a versatile treatment for hair loss.
September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” This study identified a mutation in the CST6 gene linked to a rare syndrome with symptoms affecting hair and skin, revealing cystatin M/E's role in maintaining epidermal homeostasis and hair follicle development.
April 2018 in “Journal of Investigative Dermatology” This study found that TGFbeta is a key pathway causing age-related loss of dermal fat's antimicrobial function, suggesting that targeting TGFBR might help restore skin defense against infections in older age.
August 2016 in “PolyPublie (École Polytechnique de Montréal)” This study observed early cardiac effects in young minipigs following high-dose doxorubicin chemotherapy, with a decrease in heart function and changes in cardiac MRI measurements compared to controls.
This dissertation reported that the loss of Ovol2 impairs hair follicle regeneration and wound repair in mice, highlighting its role in regulating directional migration of epithelial cells.
74 citations
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January 2020 in “IEEE Access” This study reports that the ScalpEye system accurately diagnosed dandruff, folliculitis, hair loss, and oily hair with a precision range of 97.41% to 99.09%.
36 citations
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February 2018 in “British Journal of Dermatology” In this study, researchers found that eccrine sweat glands in human scalp skin are morphologically integrated into the pilosebaceous unit, suggesting they form a common homeostatic tissue environment with adjacent structures.
31 citations
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October 2019 in “Genes & Diseases” This study identified significant gene expression differences in human basal cell carcinoma, including up-regulation of zinc finger encoding genes, which are not entirely reflected in current mouse models.
31 citations
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June 2017 in “Regeneration” This study found that applying BMP2 stimulated limited regeneration of the amputated P2 bone in mice, but only when applied during a specific "regeneration window" after injury.
13 citations
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September 2022 in “Frontiers in immunology” This study found that Ifidancitinib, a JAK1/3 inhibitor, significantly promoted hair regrowth and reduced inflammation in a mouse model of alopecia areata by decreasing pathogenic T cell activity and inducing T cell exhaustion.
10 citations
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July 2023 in “Pharmaceuticals” This study explored the wound healing potential of a natural marine soft coral-derived nanoparticle-based gel in a diabetic excision wound model, finding it effectively regulates proinflammatory cytokines and inhibits enzymes related to wound healing.
9 citations
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January 2025 in “Droplet” This review explores recent advancements in precise cell manipulation technologies, detailing the status, principles, benefits, limitations, and future potential of methods like single-cell manipulation and 3D bioprinting for cells and tissue engineering.
9 citations
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December 2024 in “Nano Research” In a study on diabetic mice, researchers developed a protein-based hydrogel that leverages zinc ions and the natural compound phellopterin to promote cutaneous nerve regeneration, angiogenesis, and tissue remodeling in diabetic wounds, highlighting its potential for advanced wound therapy.
7 citations
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October 2024 in “Pharmaceutics” This study found that clindamycin-loaded PHA nanoparticles showed potent antibacterial effects against MRSA and enhanced wound healing in a mouse model of MRSA-infected wounds, indicating their potential as a novel treatment for these infections.