research A Matter of Life and Death: Self-Renewal in Stem Cells
Stem cell self-renewal is complex and needs more research for full understanding.
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research Microneedles as the Technique of Drug Delivery Enhancement in Diverse Organs and Tissues
Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.
research The Disintegrin/Metalloproteinase Adam10 Is Essential for Epidermal Integrity and Notch-Mediated Signaling
Adam10 enzyme is crucial for healthy skin and proper Notch signaling.
research Maternal PPARγ Protects Nursing Neonates by Suppressing the Production of Inflammatory Milk
A mother's PPARγ is crucial for preventing harmful milk that can cause inflammation and growth problems in babies.
research A Review of Aging and an Examination of Clinical Methods in the Assessment of Aging Skin. Part 2: Clinical Perspectives and Methods
The document concludes that various clinical methods are used to assess ageing skin and the effectiveness of anti-ageing products.
research Cortical Cell Types and Intermediate Filament Arrangements Correlate with Fiber Curvature in Japanese Human Hair
Hair curvature in Japanese people is linked to specific cell types and filament arrangements in the hair cortex.
research Extracellular Matrix as a Regulator of Epidermal Stem Cell Fate
The extracellular matrix is crucial for controlling skin stem cell behavior and health.
research Engineering Pro-Regenerative Hydrogels for Scarless Wound Healing
Hydrogels could lead to better treatments for wound healing without scars.
research BLIMP1 Is Required for Postnatal Epidermal Homeostasis but Does Not Define a Sebaceous Gland Progenitor Under Steady-State Conditions
BLIMP1 is essential for skin maintenance but not for defining sebaceous gland progenitors.
research Trichohyalin: Presence in the Granular Layer and Stratum Corneum of Normal Human Epidermis
Trichohyalin is also found in the outer layers of normal human skin.
research Novel TMEM173 Mutation and the Role of Disease-Modifying Alleles
A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.
research Investigation of Follicular and Non-Follicular Pathways for Polyarginine and Oleic Acid-Modified Nanoparticles
Surface-modified nanoparticles mainly use non-follicular pathways to enhance skin permeation of ibuprofen and could improve treatment for inflammatory skin diseases.
research Expression Patterns of MITF During Human Cutaneous Embryogenesis: Evidence for Bulge Epithelial Expression and Persistence of Dermal Melanoblasts
Melanocyte precursors in human fetal skin follow a specific migration pattern and some remain in the skin's deeper layers.
research Localization of Plasminogen Activator Inhibitor Type 2 in Hair and Nail: Implications for Terminal Differentiation
PAI-2 helps in the maturation and protection of hair and nail cells.
research Doping-Control Analysis of the 5α-Reductase Inhibitor Finasteride: Determination of Its Influence on Urinary Steroid Profiles and Detection of Its Major Urinary Metabolite
Finasteride affects urinary steroid profiles and can potentially hide steroid abuse in sports drug testing.
research Genetically-Manipulated Adult Stem Cells as Therapeutic Agents and Gene Delivery Vehicles for Wound Repair and Regeneration
Genetically-altered adult stem cells can help in wound healing and are becoming crucial in regenerative medicine and drug design.
research As a Carrier–Transporter for Hair Follicle Reconstitution, Platelet-Rich Plasma Promotes Proliferation and Induction of Mouse Dermal Papilla Cells
Platelet-rich plasma can help grow more mouse hair follicles, but it doesn't work for human hair follicles yet.
research A Systematic Summary of Survival and Death Signaling During the Life of Hair Follicle Stem Cells
The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.
research Adipose Stem Cells Isolated From Diabetic Mice Improve Cutaneous Wound Healing In Streptozotocin-Induced Diabetic Mice
Fat stem cells from diabetic mice can help heal skin wounds in other diabetic mice.
research Topobiology of Human Pigmentation: P-Cadherin Selectively Stimulates Hair Follicle Melanogenesis
P-cadherin is crucial for hair follicle pigmentation but not skin pigmentation.
research Injectable Self-Healing Ceria-Based Nanocomposite Hydrogel with ROS-Scavenging Activity for Skin Wound Repair
The hydrogel speeds up skin wound healing and helps regenerate tissue.
research Essential Role of Polarity Protein Par3 for Epidermal Homeostasis Through Regulation of Barrier Function, Keratinocyte Differentiation, and Stem Cell Maintenance
The protein Par3 is crucial for healthy skin, affecting the skin barrier, cell differentiation, and stem cell maintenance.
research Wanted, Dead and Alive: Why a Multidisciplinary Approach Is Needed to Unlock Hair Treatment Potential
Different fields of expertise must work together to better understand hair growth and create effective hair loss treatments.
research Yellow and Orange in Cutaneous Lesions: Clinical and Dermoscopic Data
Yellow and orange colors are important for diagnosing certain skin conditions.
research Novel Aspects of Age-Protection by Spermidine Supplementation Are Associated with Preserved Telomere Length
Spermidine helps protect against aging by preserving telomere length.
research Alteration of Skin Wound Healing in Keratinocyte-Specific Mediator Complex Subunit 1 Null Mice
MED1 affects skin wound healing differently in young and old mice.
research Accelerated Senescence in Skin in a Murine Model of Radiation-Induced Multi-Organ Injury
High-dose radiation speeds up aging in skin stem cells.
research Adaptive Gelatin Microspheres Enhanced Stem Cell Delivery and Integration With Diabetic Wounds to Activate Skin Tissue Regeneration
Gelatin microspheres with stem cells speed up healing in diabetic wounds.
research Comparison of the Therapeutic Effect of Allogeneic and Xenogeneic Small Extracellular Vesicles in Soft Tissue Repair
Both human and animal-derived small extracellular vesicles speed up skin healing equally well.
research Major Improvement in Wound Healing Through Pharmacologic Mobilization of Stem Cells in Severely Diabetic Rats
A new therapy sped up wound healing and reduced scarring in diabetic rats.