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The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

The document concludes that managing female hyperandrogenism requires a combination of identifying the cause, lifestyle changes, medication, and cosmetic treatments.

Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

Nonclassic congenital adrenal hyperplasia is a genetic disorder causing hormone imbalances, affecting fertility and requiring personalized treatment.

Sex steroids produced in the hippocampus are crucial for brain functions like memory and learning in rodents.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Minoxidil and finasteride effectively treat hair loss.

New genes and pathways are important for testosterone production and male sexual development.

A woman's hair loss and other symptoms were due to a rare hormone deficiency treatable with steroids.

The conclusion is that young women with excessive hair growth should be quickly tested for hormonal issues and treated to improve their social well-being.

Cocaine impairs male sexual behavior and alters testosterone metabolism in the brain.

Men with androgenetic alopecia have oilier and less hydrated scalps, especially in sensitive areas.

No significant link between hair loss and iron or thyroid levels was found, but checking for deficiencies might still be useful.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

Birth control pills with low-dose estrogen and antiandrogenic progestins can effectively treat acne.

Acne can be managed with various treatments and requires psychological support due to its emotional impact.

Acne can't be cured but can be managed with treatments like benzoyl peroxide and diet changes; it's costly and can lead to scarring and mental health issues.

Nonclassic adrenal hyperplasia is a genetic condition that can cause early puberty and fertility problems, treated with specific steroids.

Local skin glucocorticoid production is crucial for healthy skin, and its disruption can lead to skin diseases.

Rare adrenal cancers that secrete androgens or estrogens have a poor prognosis and are treated primarily with surgery.

PCOS is a complex disorder in women that can lead to various health risks and requires personalized treatment.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.