July 2024 in “Journal of the American Academy of Dermatology” Low-dose oral minoxidil is generally safe for hypertensive patients with hair loss.
June 2024 in “Journal of Allergy and Clinical Immunology” TSLP affects atopic dermatitis by increasing sebum and reducing fat through IL-4/IL-13 signaling.
November 2023 in “Journal of Investigative Dermatology” γδTregs can protect hair follicles from alopecia areata and may help regrow hair.
October 2023 in “CHEST Journal” Early recognition and treatment of severe SLE symptoms can improve outcomes.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Key skin cell regulators and gene organization changes are crucial for skin cell development and could help treat skin disorders.
May 2022 in “Journal of The American Academy of Dermatology” Low-dose oral minoxidil often improves hair loss, and early treatment of traction alopecia is effective but harder if delayed.
September 2017 in “Journal of Investigative Dermatology” Aging causes sweat glands to shrink, leading to skin issues, and blue light can help hair grow.
September 2017 in “Journal of Investigative Dermatology” Activating the hexosamine pathway can improve skin health and increase hair follicle stem cells.
November 2016 in “Journal of The American Academy of Dermatology” Control symptoms and use safe treatments for skin conditions like lichen planopilaris and chronic cutaneous lupus erythematosus.
May 2015 in “Journal of The American Academy of Dermatology” Oral minoxidil effectively increases hair growth in male baldness but can cause side effects like excessive hair growth and swelling.
September 2012 in “African Journal of Urology” Testosterone replacement therapy improves libido, mood, muscle strength, and bone density in men with Testosterone Deficiency Syndrome.
March 2012 in “Journal of Pediatric and Adolescent Gynecology” Doctors vary in how they initially test for PCOS, but most agree on using oral contraceptives and lifestyle changes as first treatments.
November 2010 in “Value in Health” Real-life dosing of biologics for plaque psoriasis often deviates from recommended guidelines, especially for high-need patients.
February 1999 in “The anatomical record” Two mouse mutants have defective hair cuticle cross-linking.
688 citations,
June 2007 in “Cell Stem Cell” Removing the ATR gene in adult mice causes rapid aging and stem cell loss.
578 citations,
April 1993 in “Cell” TGFα gene mutation in mice causes abnormal skin, wavy hair, curly whiskers, and sometimes eye inflammation.
356 citations,
March 2012 in “Trends in Plant Science” Auxin and ethylene hormones both work together and against each other to control plant growth.
252 citations,
January 2008 in “Trends in Endocrinology and Metabolism” Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.
236 citations,
July 2001 in “Trends in Molecular Medicine” Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.
228 citations,
September 2012 in “Trends in Neurosciences” Nerves are crucial for the regeneration of various body parts in many animals.
189 citations,
May 1999 in “Microscopy Research and Technique” Neurotrophins, especially NGF, are crucial for pain development and management.
162 citations,
January 2015 in “Trends in Endocrinology and Metabolism” Women with PCOS face higher risks of diabetes and heart disease, and these risks increase with obesity.
153 citations,
October 2007 in “Cell Stem Cell” New research suggests that skin cell renewal may not require a special type of cell previously thought to be essential.
148 citations,
May 2012 in “The American Journal of Human Genetics” Cantú syndrome is caused by mutations in the ABCC9 gene.
124 citations,
June 2020 in “Cell Stem Cell” Fat cells in the skin help start healing and form important repair cells after injury.
119 citations,
November 2014 in “Trends in Cell Biology” Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.
118 citations,
October 2013 in “Trends in Genetics” The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.
105 citations,
April 2014 in “Trends in Pharmacological Sciences” Targeting the Smoothened receptor shows promise for treating certain cancers.
98 citations,
July 2014 in “Trends in Molecular Medicine” Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.
80 citations,
April 2018 in “Trends in Molecular Medicine” Lichen Planopilaris and Frontal Fibrosing Alopecia may help us understand hair follicle stem cell disorders and suggest new treatments.