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This narrative review highlights the critical role of intracrine hormone production in peripheral tissues, suggesting that continuous-release subcutaneous testosterone pellet therapy may offer a more effective symptom-driven approach for aging populations, though large-scale randomized controlled trials are needed for confirmation.

This study found that among women with polycystic ovary syndrome, higher age, obesity, hirsutism, and having children were independently associated with increased metabolic risk.

This chapter reviews hyperadrenocorticism in ferrets, covering its causes, symptoms, diagnosis, and treatment options, but reports no new research findings.

This study found that about 80% of known fullerene-binding proteins rank in the top 10% of scorers for C60 docking sites, confirming the accuracy of the predictive model used.

Finasteride helps regrow hair and shrink prostate by reducing DHT, with some sexual side effects.

This review discusses clinical, hormonal, and genetic aspects of nonclassic adrenal hyperplasia and reports no new findings; the condition is highlighted as a potential cause of premature adrenarche and other symptoms in young people.

This study found that long-term flutamide treatment reduced hair loss in women with female pattern hair loss, but liver-related dropouts were minimized at a very low dose of 62.5 mg/day.

This study found that fasting insulin levels are associated with increased cardiovascular and metabolic risk factors in women with polycystic ovary syndrome.

This study found that the pH dependency of rat steroid 5α-reductase type II isozyme significantly affects its kinetic properties, including Vmax and Km, suggesting past discrepancies in literature may arise from these pH variances during assays.

This article discusses the various roles of steroids in vertebrate organ systems and notes several glucocorticoids that were among the Top 200 Drugs by sales in the 2010s, but it reports no new clinical findings.

In this study, the ChatGPT-5 model accurately answered 76.47% of questions on the Polish endocrinology specialty exam, surpassing the 60% passing threshold, yet its role in clinical decision-making remains uncertain, highlighting the need for further research.

This case series observed the efficacy of GnRH analogues in diagnosing and treating various forms of ovarian hyperandrogenism, illustrating their role in symptom management without surgery, particularly for benign conditions and refractory androgen excess.

In this study, 85.9% of 120 hirsute Saudi women exhibited elevated androgen levels, suggesting the need for a comprehensive hormonal evaluation to identify underlying causes of hirsutism.

This review found that platelet-rich plasma therapy may enhance ovarian repair and fertility outcomes in ovarian insufficiency, but notes that optimal usage and long-term effects require further investigation.

This review identifies and discusses various endocrine-related causes of hypertension in children and adolescents, emphasizing the role of genetic predispositions and highlighting the need for systematic diagnostic guidelines and genetic sequencing referrals to improve diagnosis and treatment strategies.

This case report highlights a rare instance of postmenopausal virilization in a 71-year-old woman due to coexisting ovarian hilus cell hyperplasia and a Sertoli-Leydig cell tumor.

This research found that androgen bioactivity plays a role in normal female sexual differentiation, suggesting females develop within a significant androgenic environment, with implications for understanding conditions like congenital adrenal hyperplasia.

In this study, hormonal abnormalities were detected in all investigated hirsute Saudi women, with elevated major androgens in 85.9% and polycystic ovaries in 59% of cases.

In this study, cross-sex hormone therapy affected hair growth patterns differently, with estrogen reducing hair growth in male-to-female transsexuals and testosterone increasing it in female-to-male transsexuals; however, male typical hair diameters were not fully reached in the latter group after 12 months.

This study suggests that cerebrospinal fluid levels of the neurosteroids allopregnanolone and pregnanolone correlate negatively with PTSD and negative mood symptoms, with potential sex-specific differences in synthesis enzyme blocks.

This review highlights that idiopathic hirsutism is characterized by local hyperandrogenization affecting hair growth, without other signs of hyperandrogenism, and shows no new results; racial differences in prevalence are noted but not in androgenic steroids.

This review discusses idiopathic hirsutism, potential underlying mechanisms, and various therapeutic approaches without providing new clinical results, and emphasizes the need for further research on well-defined patient groups.

In this study, finasteride altered acute ethanol withdrawal severity differently in male and female mice, highlighting sex differences in sensitivity to changes in neurosteroid levels.

In this review, the role of DHT in male-type obesity and metabolic diseases is discussed, with increased levels potentially exacerbating cardiovascular disease risk; the paper reports no new results.

This review discusses the role of neurosteroids and androgens throughout different life stages, noting the potential disruptions caused by 5α-reductase inhibitors like finasteride, but no new clinical results are reported.

This study found that 4-MA is a potent inhibitor of testosterone 5α-reductase in human tissues, promising potential for treating androgen-dependent skin conditions like male pattern baldness.

This study discusses the complex roles and effects of brain-synthesized sex neurosteroids, highlighting sex differences in their concentrations and their varied impacts on synaptic plasticity, cognitive behavior, and aging-related cognitive decline.

This article outlines common and serious causes of excessive body hair in women, noting that benign conditions like polycystic ovarian syndrome are treatable, while dangerous causes require swift medical attention; it reports no new results.

This review explores finasteride's effects on neuroactive steroid levels and their potential influence on disorders like depression and alcohol withdrawal but reports no new clinical findings.

This review discusses the use of anabolic-androgenic steroids in sports and outlines current methods for detecting urinary steroid doping, particularly testosterone, but reports no new experimental findings.