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    Did you mean Androstanediol Glucuronide?
    Glossary Androstanediol Glucuronide

    metabolite of dihydrotestosterone linked to hair loss and hirsutism

    Androstanediol Glucuronide (3α-Diol G) is a metabolite of dihydrotestosterone (DHT), a potent androgen hormone. It is often measured in clinical settings to assess androgen activity in the body, as elevated levels can be associated with conditions like androgenic alopecia (hair loss) and hirsutism (excessive hair growth).

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    1. Evidence of Increased 3‐Alpha‐Androstanediol Glucuronide in Female Pattern Alopecia: A Cross‐Sectional Observational Study Evaluating Ovarian, Adrenal, and Peripheral Androgens International Journal of Dermatology · 2026
    2. 3 alpha, 17 beta-androstanediol glucuronide in plasma. A marker of androgen action in idiopathic hirsutism. 1982 · 179 citations
    3. Female androgenic alopecia. The 3 alpha,17 beta-androstanediol glucuronide/sex hormone binding globulin ratio as a possible marker for female pattern baldness Archives of Dermatology · 1986 · 13 citations
    4. Is 3α, 17β-androstanediol-glucuronide a diagnostic marker in women with androgenic manifestations? Gynecological Endocrinology · 1992 · 3 citations
    5. Correlation of Serum 3<i>α</i>-Androstanediol Glucuronide with Acne and Chest Hair Density in Men The Journal of Clinical Endocrinology & Metabolism · 1988 · 51 citations
    6. Clinical Usefulness of Plasma Androstanediol Glucuronide Measurements in Women with Idiopathic Hirsutism* 1987 · 66 citations
    7. The biochemical and phenotypic characterization of females homozygous for 5 alpha-reductase-2 deficiency. The Journal of Clinical Endocrinology & Metabolism · 1995 · 54 citations
    8. Clinical and Biochemical Parameters of Androgen Action in Normal Healthy Caucasian<i>Versus</i>Chinese Subjects The Journal of Clinical Endocrinology & Metabolism · 1991 · 177 citations
    9. Alterations in androgen conjugate levels in women and men with alopecia Fertility and Sterility · 1994 · 24 citations
    10. Androgen metabolism in hirsute patients treated with cyproterone acetate 1984 · 64 citations
    11. 6 Peripheral androgens and the role of androstanediol glucuronide Clinics in endocrinology and metabolism · 1986 · 57 citations
    12. Clinical and hormonal effects of the 5 alpha-reductase inhibitor finasteride in idiopathic hirsutism The Journal of Clinical Endocrinology and Metabolism · 1994 · 17 citations
    13. Clinical relevance of testosterone and dihydrotestosterone metabolism in women ˜The œAmerican journal of medicine · 1995 · 31 citations
    14. The 5 Alpha-Reductase Isozyme Family: A Review of Basic Biology and Their Role in Human Diseases Advances in Urology · 2011 · 218 citations
    15. Predominant expression of 5 alpha-reductase type 1 in pubic skin from normal subjects and hirsute patients. 1996 · 11 citations
    16. A Role for Steroid 5 alpha-reductase 1 in Vascular Remodelling During Endometrial Decidualisation bioRxiv (Cold Spring Harbor Laboratory) · 2022
    17. The 5alpha-reductase type 1, but not type 2, gene is expressed in anagen hairs plucked from the vertex area of the scalp of hirsute women and normal individuals Brazilian Journal of Medical and Biological Research · 2003 · 17 citations
    18. Urinary steroids in women with androgenic alopecia Clinical Biochemistry · 2000 · 16 citations
    19. Idiopathic Hirsutism* Endocrine Reviews · 2000 · 47 citations
    20. Hormone therapy in acne Indian Journal of Dermatology, Venereology and Leprology · 2013 · 24 citations
    21. 12 Treatment of hirsutism with 5α-reductase inhibitors Clinics in endocrinology and metabolism · 1986 · 28 citations
    22. Steroidogenic Isoenzymes in Human Hair and Their Potential Role in Androgenetic Alopecia Dermatology · 2003 · 31 citations
    23. ADT-G as a promising biomarker for peripheral hyperandrogenism in adult female acne Dermato-endocrinology · 2017 · 6 citations
    24. Gender Differences in Production and Circulating Levels of Sex Hormones and Their Impact on Aging Skin Springer eBooks · 2014
    25. Evidence for Increased 5α-Reductase Activity During Early Childhood in Daughters of Women With Polycystic Ovary Syndrome The Journal of Clinical Endocrinology & Metabolism · 2016 · 40 citations
    26. An Update of Congenital Adrenal Hyperplasia Annals of the New York Academy of Sciences · 2004 · 151 citations
    27. Dermatologic Manifestations of Polycystic Ovary Syndrome American Journal of Clinical Dermatology · 2007 · 76 citations
    28. Hirsutism and virilization Postgraduate medicine · 1995 · 13 citations
    29. [Clinical significance of testosterone and dihydrotestosterone metabolism in women]. PubMed · 1996
    30. Clinical biochemistry of dihydrotestosterone Annals of Clinical Biochemistry · 2013 · 50 citations