14 citations
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January 2017 in “Annals of Dermatology” In this retrospective study, low-dose methotrexate was observed to be effective and well-tolerated in treating recalcitrant alopecia areata multiplex, achieving complete or near-complete hair regrowth in about 90% of patients despite some experiencing elevated liver enzymes and gastrointestinal discomfort.
8 citations
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March 2020 in “Aesthetic Plastic Surgery” Finasteride and minoxidil together safely and effectively increase hair growth and density for androgenetic alopecia.
5 citations
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July 2018 in “Pediatrics” This case report describes a previously healthy 3-year-old girl who developed scurvy symptoms not directly linked to vitamin C dietary deficiency, highlighting the potential for misdiagnosis in similar cases.
1 citations
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March 2024 in “Pathogens” The systematic review reports an association between Beau’s lines and COVID-19 infection or vaccination, observing variability in onset and resolution times, and suggesting these nail disorders might indicate previous severe infection or vaccination, as well as potentially signify long COVID-19 syndrome.
February 2026 in “British Journal of Sports Medicine” Transgender women have similar fitness to cisgender women, while transgender men have higher fat and lower strength than cisgender men; hormone therapy affects body composition and strength.
March 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study found that the combination of lithium and zinc demonstrated significant transcriptomic rescue in three datasets, with consistent results across methodologies, suggesting its potential targeting of DP-specific pathways.
March 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study found that the combination of lithium and zinc produced a statistically significant transcriptomic rescue across three datasets, with the strongest signal observed in a DP-enriched model, suggesting potential efficacy in targeting DP-specific pathways.
January 2025 in “HORMONES” This systematic review reported positive outcomes with gender-affirming hormone therapy in Canada and emphasized the urgent need for standardized outcome measurement tools to enhance evidence-based practices.
November 2022 in “Research Square (Research Square)” This meta-analysis suggests a significant association between the use of facial sunscreen and moisturizer and frontal fibrosing alopecia, while finding no significant relationship with hair products or treatments.
128 citations
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February 2016 in “British Journal of Dermatology” This study found that patients with alopecia areata experience significant impairments in health-related quality of life, notably affecting mental health, according to various quality of life assessment tools.
1 citations
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March 2022 in “medRxiv (Cold Spring Harbor Laboratory)” This study found that women with PCOS have a significant risk of mental health disorders, including depression and anxiety, but results varied due to methodological differences, and ethnic disparities were not well-examined.
December 2023 in “Research Square (Research Square)” This study observed that individuals with Down syndrome had a higher incidence of autoimmune skin conditions and a lower incidence of certain viral infections, indicating unique immune system dysregulation.
May 2026 in “Aesthetic Plastic Surgery” This study found that autologous growth factor injections for androgenetic alopecia improved hair density, thickness, and patient satisfaction over 12 months; however, high bias risk and non-standardized methods limit the evidence's reliability, highlighting the need for larger, standardized trials.
January 2023 in “Dermatologic therapy” This study reports that diphenylcyclopropenone topical immunotherapy resulted in any hair regrowth for 69% of patients with alopecia areata, but with common side effects including mild to severe contact dermatitis.
57 citations
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March 2011 in “The American Journal of Dermatopathology” This study found that permanent alopecia can occur after certain chemotherapy treatments and presents as nonscarring hair loss similar to androgenetic alopecia, with specific histological features that could be misdiagnosed without proper clinicopathological correlation.
23 citations
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February 2021 in “Dermatologic therapy” This study found that pentoxifylline plus topical corticosteroids had the highest treatment success rate for alopecia areata compared to no treatment, but the best overall treatment remains uncertain due to varying data.
5 citations
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July 2024 in “Minerva Endocrinology” In this systematic review, an increase in hemoglobin and hematocrit was associated with testosterone therapy, especially within the first year, and factors like serum testosterone levels and therapy specifics were linked to erythrocytosis development, highlighting the need for further research to guide clinical practice.
This study observed that in a real-world clinical setting in Greece, belimumab effectively controlled disease activity in lupus patients and allowed for a reduction in glucocorticoid dosage, with more pronounced benefits seen in patients who were serologically active at the start of treatment.
1 citations
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May 2025 in “The Journal of Rheumatology” This study reviewed how Anifrolumab, though often used in real-world settings for SLE patients with neurological symptoms, showed varying effectiveness and required cautious monitoring for adverse effects like thrombocytopenia and cerebrovascular events.
1 citations
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May 2022 in “Frontiers in Psychiatry” In this case study, a 33-year-old female with neuropsychiatric systemic lupus erythematosus experienced hair regrowth with no further loss after receiving a combination of systemic and local treatments.
This study reports that a novel ketoconazole-loaded microneedle array significantly enhances drug delivery and retention in the skin, demonstrating improved hair growth in animal models, suggesting a promising treatment for androgenic alopecia that addresses current topical therapies' limitations.
March 2025 in “International Journal of Trichology” This study reports that low-dose oral minoxidil is generally well tolerated from a cardiovascular perspective, and serious side effects like pericardial effusion are associated with higher doses and pre-existing conditions.
January 2017 in “The Journal of Korean Medicine Ophthalmology&Otorhinolaryngology&Dermatology” This study found that early-onset male androgenetic alopecia is significantly associated with an increased risk of metabolic syndrome.
122 citations
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November 2014 in “BMC Medicine” This research observed that oral testosterone replacement therapy significantly increases cardiovascular risk, while effects of injected or transdermal therapy on cardiovascular risk were not significant, prompting further investigation into these methods.
70 citations
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February 2018 in “Seminars in Arthritis and Rheumatism” This study found that belimumab helped achieve low disease activity in over 40% of systemic lupus erythematosus patients in real-life settings, alongside reduced corticosteroid use and fewer flares.
47 citations
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June 2015 in “Medicines” This review examines the use and efficacy of Panax ginseng in various clinical settings, noting that clinical trial outcomes vary widely based on study conditions and ginseng types; no new results are reported.
36 citations
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September 2019 in “Journal of Herbal Medicine” This review explores research on nanoformulations for enhancing the topical delivery of herbal medicines, noting potential benefits like improved bioavailability and sustained delivery, and emphasizes the need for safety and toxicity guidelines in developing these novel drug delivery systems.
28 citations
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February 2007 in “Cancer Research” This study found that inhibiting C/EBP transcription factors in mouse skin reduced papilloma formation and caused systemic hair loss, suggesting C/EBP may be a potential therapeutic target.
17 citations
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January 1997 in “Cell and Tissue Research” This study found that a serum-free DMEM-F12 medium with 45% oxygen best supports in vitro development and differentiation of human fetal skin, closely mimicking the in vivo state.
14 citations
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March 2018 in “Current Drug Delivery” In this study, researchers reviewed literature on topical delivery of finasteride for androgenetic alopecia, finding that liposomal gels with specific additives showed the highest skin permeation rates, suggesting potential for reducing systemic side effects compared to oral formulations.