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Too much Smad7 changes skin and hair development by breaking down a protein called β-catenin, leading to more oil glands and fewer hair follicles.

Finasteride safely lowers DHT levels without affecting testosterone.

Cathepsin L is essential for normal hair growth and development.

Use minoxidil for hair loss treatment; assess results after 6 months.

Cancer cells often have more copies of TERT and TERC genes, which helps them grow and could affect patient outcomes.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Young adults have about 230,000 tactile nerve fibers, decreasing 5-8% per decade with age.

Postpartum depression is linked to changes in brain chemicals, inflammation, stress, and certain genes, and can potentially be identified by markers like specific steroids, serotonin levels, and vitamin D levels.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Masculine facial features may not reliably indicate heritable health, and more research is needed.

Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.

Matriptase is crucial for keeping epithelial tissues healthy and functioning properly.

Some vitamins and minerals like vitamin D and iron can help with certain types of hair loss, but more research is needed for others.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.

Hair analysis can detect cocaine use but doesn't accurately show the amount or timing of use.

Probiotic bacteria improved skin and hair health in aged mice.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Isotretinoin effectively treats severe acne and similar conditions, but has common, mostly reversible side effects, requiring careful patient monitoring.

Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.

Substances from Chinese medicines show promise for immune support and disease prevention, but the way they are processed affects their effectiveness.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

No single treatment is consistently effective for alopecia areata, and more research is needed.

Eclipta alba extract may help hair grow similarly to Minoxidil.

Potassium channel openers could help treat cardiovascular diseases and asthma but require better targeting to specific tissues for effective use.

Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.

Exposure to finasteride in the womb caused lasting reproductive issues in male rats.

Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.