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The research shows that hydrogen bonds greatly affect the crystal structure of a Finasteride derivative.

5AR inhibitors like finasteride and dutasteride improve hair growth and slow hair loss in male pattern baldness.

The document explains how to make a compound called 3.BETA.-Benzoyloxy-4-pregnen-16.ALPHA.,17.ALPHA.-epoxy-6,20-dione and describes its crystal structure.

A new compound was made that might help treat diseases related to male hormones.

Inhibitors of the enzyme 5 alpha-reductase could potentially treat disorders like prostate cancer and baldness.

Finasteride almost fully depletes allopregnanolone in rat brains and enhances 20α-DHP, but doesn't change 3α-DHP levels.

Black pepper leaf extract contains compounds that can block testosterone effects and promote hair growth.

Some new progesterone derivatives are better at blocking testosterone conversion than a common drug.

Higher levels of certain proteins in hair loss areas may help understand and treat hair loss.

Alpha-blockers and 5-alpha reductase inhibitors are main treatments for BPH, with new support for phosphodiesterase-5 inhibitors and beta-3 agonists.

Canadian lawsuits involving 5-alpha-reductase inhibitors are related to persistent erectile dysfunction side effects, with no judgments against companies yet.

New pregnane derivatives are effective at inhibiting an enzyme linked to hair loss and reducing oil gland activity.

Older patients sticking to their prostate medication saw lasting health benefits.

Mexican patients had a lower incidence of skin reactions to drugs and no significant link between these reactions and the TNF2 gene variant.

The new saw palmetto extract effectively inhibits an enzyme linked to prostate enlargement and may be as good as standard treatments.

Intralesional methotrexate effectively treats alopecia areata by reducing TNF-α levels, leading to hair regrowth.

Estrogen deficiency can reduce the enzyme activity needed to activate vitamin D.

5-alpha reductase inhibitors are generally safe but can cause sexual side effects and require patient education on risks.

5-alpha-reductase inhibitors may help stabilize or slow down hair loss in some frontal fibrosing alopecia patients, but more research is needed to confirm their effectiveness and safety.

Some curcumin-like compounds can effectively and safely block the enzyme linked to hair loss and other conditions related to male hormones.

The protein interleukin-1 alpha helps regenerate hair follicles and increase stem cell growth in mice.

5-Alpha-Reductase inhibitors shorten COVID-19 recovery time in men.

Some cannabinoid derivatives may be more effective than current drugs at targeting proteins relevant to prostate cancer treatment.

Most legal cases about 5α-reductase inhibitors, drugs for hair loss and prostate issues, complain about side effects and delayed cancer diagnosis, with most lawsuits settled out of court.

Finasteride 5mg daily is the most effective for female pattern hair loss, with higher doses of treatments generally more effective.

Eclipta alba extract could be a promising natural treatment for hair loss.

Dutasteride use can lead to a stable decline in sexual function that is not affected by age or prostate size.

IL-1 alpha stops hair follicle growth and hair production.

5-alpha reductase inhibitors can cause sexual, neurologic, endocrine, and cardiovascular side effects, but these are rare and usually stop after ending treatment.

Some drugs used to treat inflammation may cause hair loss.