7 citations,
March 2022 in “Scientific reports” Removing anthrax toxin receptor 1 in pigs prevents Senecavirus A infection and causes a rare disease similar to GAPO syndrome.
2 citations,
April 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” The skin's basement membrane is specially designed to support different types of connections between skin layers and hair follicles.
December 2017 in “Elsevier eBooks” The vitamin D receptor helps maintain hair and bone health even without binding vitamin D.
No treatment alters the natural progression of alopecia areata, and effectiveness varies, with some possibly working better in children.
162 citations,
August 2002 in “Survey of Ophthalmology” Latanoprost can make eyelashes longer, thicker, and darker.
62 citations,
April 2009 in “British Journal of Dermatology” Epidermal stem cells could lead to new treatments for skin and hair disorders.
60 citations,
June 2019 in “Ageing Research Reviews” Fat from the body can help improve hair growth and scars when used in skin treatments.
53 citations,
May 2010 in “Journal of Cellular Physiology” Mice without Vitamin D receptors have hair growth problems because of issues in the hedgehog signaling pathway.
50 citations,
November 2010 in “Plastic and Reconstructive Surgery” Botox increased hair count in men with baldness and might work by improving scalp blood flow.
28 citations,
January 2008 in “Journal of medical investigation” Sp6 promotes tooth development by reducing follistatin levels.
22 citations,
May 2021 in “Nature Communications” Tissue stiffness affects hair follicle regeneration, and Twist1 is a key regulator.
12 citations,
March 2019 in “Lasers in Surgery and Medicine” Low-level laser therapy improves hair growth and dermal papilla cell function.
9 citations,
January 2005 in “Experimental dermatology” Melatonin receptors in hair follicles help regulate hair growth and could treat hair loss.
6 citations,
April 2015 in “Behavioural Brain Research” Finasteride worsens stress effects on sensory processes, possibly linking to anxiety/depression.
5 citations,
January 2021 in “Skin appendage disorders” Smoking is linked to more hair loss and premature graying compared to nonsmokers.
4 citations,
January 2019 in “Elsevier eBooks” Finding new uses for existing drugs is promising and can lead to safer, more effective medicines.
2 citations,
September 2022 in “Frontiers in veterinary science” Certain long non-coding RNAs are important for the growth of hair follicles in Inner Mongolian cashmere goats.
140 citations,
April 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” The enzyme 25 Hydroxyvitamin D 1 α-Hydroxylase is essential for healthy skin and recovery after skin damage.
34 citations,
December 2009 in “The International Journal of Developmental Biology” Too much thymosin beta4 causes weird teeth and more hair growth in mice.
30 citations,
April 2020 in “Stem Cell Research & Therapy” PI3K/Akt pathway is crucial for hair growth and regeneration.
25 citations,
June 2018 in “Journal of The American Academy of Dermatology” Genes linked to fibrosis are more active in people with central centrifugal cicatricial alopecia.
13 citations,
August 2018 in “Journal of Molecular and Cellular Cardiology” Finasteride improves heart function and repairs damage after heart attack in mice.
5 citations,
July 2022 in “Orphanet journal of rare diseases” RSPO1 mutations in certain patients lead to skin cells that don't develop properly and are more likely to become invasive, increasing the risk of skin cancer.
76 citations,
January 2010 in “Journal of bone and mineral metabolism” 37 citations,
May 2018 in “Frontiers in physiology” Certain RNA molecules are important for the development of wool follicles in sheep.
9 citations,
June 2023 in “Cells” Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.
3 citations,
November 2022 in “European Journal of Human Genetics” New models predict male pattern baldness better than old ones but still need improvement.
65 citations,
August 2013 in “Acta Biomaterialia” The new matrix improves skin regeneration and graft performance.
54 citations,
January 2023 in “Signal Transduction and Targeted Therapy” New therapies are being developed that target integrin pathways to treat various diseases.
29 citations,
June 2020 in “International Journal of Molecular Sciences” Notch signaling disruptions can cause various skin diseases.