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    Did you mean Androstanediol Glucuronide?
    Glossary Androstanediol Glucuronide

    metabolite of dihydrotestosterone linked to hair loss and hirsutism

    Androstanediol Glucuronide (3α-Diol G) is a metabolite of dihydrotestosterone (DHT), a potent androgen hormone. It is often measured in clinical settings to assess androgen activity in the body, as elevated levels can be associated with conditions like androgenic alopecia (hair loss) and hirsutism (excessive hair growth).

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    1. The biochemical and phenotypic characterization of females homozygous for 5 alpha-reductase-2 deficiency. The Journal of Clinical Endocrinology & Metabolism · 1995 · 54 citations
    2. 3 alpha, 17 beta-androstanediol glucuronide in plasma. A marker of androgen action in idiopathic hirsutism. 1982 · 179 citations
    3. Is 3α, 17β-androstanediol-glucuronide a diagnostic marker in women with androgenic manifestations? Gynecological Endocrinology · 1992 · 3 citations
    4. Clinical and Biochemical Parameters of Androgen Action in Normal Healthy Caucasian<i>Versus</i>Chinese Subjects The Journal of Clinical Endocrinology & Metabolism · 1991 · 177 citations
    5. Alterations in androgen conjugate levels in women and men with alopecia Fertility and Sterility · 1994 · 24 citations
    6. Androgen metabolism in hirsute patients treated with cyproterone acetate 1984 · 64 citations
    7. Correlation of Serum 3<i>α</i>-Androstanediol Glucuronide with Acne and Chest Hair Density in Men The Journal of Clinical Endocrinology & Metabolism · 1988 · 51 citations
    8. Clinical and hormonal effects of the 5 alpha-reductase inhibitor finasteride in idiopathic hirsutism The Journal of Clinical Endocrinology and Metabolism · 1994 · 17 citations
    9. 6 Peripheral androgens and the role of androstanediol glucuronide Clinics in endocrinology and metabolism · 1986 · 57 citations
    10. Evidence of Increased 3‐Alpha‐Androstanediol Glucuronide in Female Pattern Alopecia: A Cross‐Sectional Observational Study Evaluating Ovarian, Adrenal, and Peripheral Androgens International Journal of Dermatology · 2026
    11. Clinical relevance of testosterone and dihydrotestosterone metabolism in women ˜The œAmerican journal of medicine · 1995 · 31 citations
    12. The 5 Alpha-Reductase Isozyme Family: A Review of Basic Biology and Their Role in Human Diseases Advances in Urology · 2011 · 218 citations
    13. Predominant expression of 5 alpha-reductase type 1 in pubic skin from normal subjects and hirsute patients. 1996 · 11 citations
    14. A Role for Steroid 5 alpha-reductase 1 in Vascular Remodelling During Endometrial Decidualisation bioRxiv (Cold Spring Harbor Laboratory) · 2022
    15. 12 Treatment of hirsutism with 5α-reductase inhibitors Clinics in endocrinology and metabolism · 1986 · 28 citations
    16. The 5alpha-reductase type 1, but not type 2, gene is expressed in anagen hairs plucked from the vertex area of the scalp of hirsute women and normal individuals Brazilian Journal of Medical and Biological Research · 2003 · 17 citations
    17. Urinary steroids in women with androgenic alopecia Clinical Biochemistry · 2000 · 16 citations
    18. Skin steroidogenesis in health and disease Reviews in endocrine and metabolic disorders · 2016 · 47 citations
    19. Idiopathic Hirsutism* Endocrine Reviews · 2000 · 47 citations
    20. Hormone therapy in acne Indian Journal of Dermatology, Venereology and Leprology · 2013 · 24 citations
    21. Steroidogenic Isoenzymes in Human Hair and Their Potential Role in Androgenetic Alopecia Dermatology · 2003 · 31 citations
    22. [Clinical significance of testosterone and dihydrotestosterone metabolism in women]. PubMed · 1996
    23. Clinical biochemistry of dihydrotestosterone Annals of Clinical Biochemistry · 2013 · 50 citations
    24. Dutasteride reduces alcohol’s sedative effects in men in a human laboratory setting and reduces drinking in the natural environment Psychopharmacology · 2014 · 32 citations
    25. Pharmakokinetik und Biokonversion von Dehydroepiandrosteron nach Dexamethason-Vorbehandlung bei Frauen mit dem Syndrom der polyzystischen Ovarien Online Publication Service of Würzburg University (Würzburg University) · 2004
    26. Randomized Placebo-Controlled Clinical Trial of Dutasteride for Reducing Heavy Drinking in Men Journal of Clinical Psychopharmacology · 2024 · 2 citations
    27. Evidence for Increased 5α-Reductase Activity During Early Childhood in Daughters of Women With Polycystic Ovary Syndrome The Journal of Clinical Endocrinology & Metabolism · 2016 · 40 citations
    28. 11α-Hydroxyprogesterone, a potent 11β-hydroxysteroid dehydrogenase inhibitor, is metabolised by steroid-5α-reductase and cytochrome P450 17α-hydroxylase/17,20-lyase to produce C11α-derivatives of 21-deoxycortisol and 11-hydroxyandrostenedione in vitro The Journal of Steroid Biochemistry and Molecular Biology · 2019 · 7 citations
    29. Normal Pubertal Development in Daughters of Women With PCOS: A Controlled Study The Journal of Clinical Endocrinology and Metabolism · 2016 · 27 citations
    30. ADT-G as a promising biomarker for peripheral hyperandrogenism in adult female acne Dermato-endocrinology · 2017 · 6 citations