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Finasteride forms three new products under acidic stress.

This study reported that using 2D solid-state NMR techniques on extensively labeled mouse fur improves resolution in detecting chemical shifts and secondary structure features, potentially aiding the analysis of the effects of commercial or therapeutic treatments on specific amino acids.

This study suggests that human keratin fiber matrix has a well-defined nano-scale grainy structure rather than being amorphous, with grain size influenced by chemical treatments, temperature, humidity, and follicle-level factors.

This study examined finasteride degradation under stress conditions, identifying three unique degradation products in acidic environments, providing insights into impurity profiling and quality control for finasteride formulations.

This study found that 2MbisP increases epidermal thickening more rapidly than atRA in rhino mice, while both compounds similarly reduce utricle size.

This article outlines the synthesis of spiro[cyclohexane‐1,2′‐[2 H ]indene] derivatives similar to known steroid 5α‐reductase inhibitors, but it does not report experimental findings.

This study suggests that topical procyanidin B-2 is safe for use as a hair growth agent, as it showed no mutagenic effects or significant irritation in a series of toxicological tests.

This study demonstrates a method to noninvasively assess lipid classes in rodent sebum via high-field proton NMR, observing significant lipid reductions in rats treated with an SCD1 inhibitor.

Minoxidil reacts to nitrosation 7 times more than phenol, mainly due to its -NH₂ groups, leading to the creation of N-nitrosominoxidil.

This study analyzed the structure and dynamics of ketoconazole, revealing how its molecular characteristics, such as spin-lattice relaxation time and chemical shift anisotropy, are influenced by π-π stacking interactions and different carbon site environments.

This study found that 42% of red yeast rice dietary supplements did not list monacolin concentrations on their labels, and only half of those that did contained the declared amounts.

This study found that certain pyrazole derivatives may serve as effective 5α-reductase inhibitors with potential use in the treatment of androgenetic alopecia, based on molecular docking analyses.

This study found that solid-state NMR combined with X-ray techniques provided critical insights into the structure and solvation of finasteride polymorphs, identifying gaps in existing patent characterizations.

This study identified natural compounds from Iris plants that showed potential as inhibitors of urease and carbonic anhydrase-II enzymes, suggesting their possible use in treating related disorders.

This study reported that newly synthesized nonsteroidal compounds were effective at inhibiting prostatic 5 alpha reductase isozyme 2, especially the compound with an N, N-diisopropylcarbamoyl substituent, suggesting potential for treating benign prostatic hyperplasia.

This study explored the structure and function of lipocalin prostaglandin D synthase, revealing its dual role in substrate catalysis and as a lipophilic ligand carrier, potentially informing future drug delivery design.

This study found that transgenic expression of COX-2 in mouse basal keratinocytes causes epidermal hyperplasia and certain dysplastic features at specific body sites.

This study found that platelet-rich plasma might support brain health by enhancing glial cell function and modulating immune responses in inflammation, indicating potential as a treatment for brain disorders.

This study found that octahydrobenzo[c]quinolizin-3-one derivatives, particularly compound 3, were potent and selective inhibitors of the enzyme 5α-reductase type 1.

This study found that a sucrose-based crosslinker can effectively straighten hair and maintain durability in high humidity and through repeated washings without affecting the hair's tensile properties or causing surface damage.

This study successfully synthesized novel cercidin analogues from Cercidophyllum japonicum, confirming their structure via NMR data. The researchers suggest these compounds could facilitate future antibiotic development by advancing structure-activity-relationship studies.

This study found that salinity stress in Arabidopsis thaliana root hairs may inhibit hair extension through changes in the tip-focused Ca(2+) gradient, while cytosolic pH remains unaffected.

In this study, the synthesis of C-4 and C-6 bridged haptens of 11 alpha-hydroxyprogesterone revealed an unexpected formation of a C-4 substituted product using a 6-bromo derivative, contrary to prior reports.

This study identified novel compounds from Bombax ceiba stem bark, including shamimicin, with potent hypotensive effects, and reported that a specific fraction had adverse effects on heart, liver, and kidneys in mice.

This review examines the impact of vitamin D signaling in extraskeletal tissues and notes that expected benefits from animal and cell studies have not been consistently replicated in human clinical trials.

This study examined the structural and biochemical mechanisms of human lipocalin prostaglandin D synthase, detailing substrate and product binding processes at the catalytic site and suggesting potential for drug delivery targeting hydrophobic molecules.

This study found that extracts from Indian gooseberry leaves showed strong antimalarial activity against Plasmodium falciparum, with low cytotoxicity, suggesting potential for developing new antimalarial drugs.

This article reviews the steps and methods involved in preparing skin tissues for three-dimensional volumetric imaging, highlighting its potential to provide detailed insights into skin structure not possible with traditional 2D histology, but reports no new findings.

This study introduced a new adaptive microrhizotron for non-destructive observation of pepper root traits, finding that specific installation patterns significantly enhanced root interception probability while effectively measuring root architecture for plant research.

This study explored new molecular structures as potential COVID-19 treatments, identifying a compound called Hit15 that inhibited viral infection in lab settings and reduced inflammation markers in human neutrophils, suggesting further development is warranted.