August 2019 in “Journal of Invertebrate Pathology” Thymosin beta 4 protects cells from damage by blocking a harmful microRNA and boosting a protective gene.
February 2019 in “bioRxiv (Cold Spring Harbor Laboratory)” The gene Prss53 affects hair shape and bone development in rabbits.
January 2015 in “Indian Journal of Medical Biochemistry” Men with early balding should be checked for metabolic syndrome, as there's a link between the two.
May 2021 in “Experimental Cell Research” FOXC1 boosts SFRP1 in hair loss, suggesting new treatments.
November 2020 in “Psychoneuroendocrinology” Finasteride might affect memory by impacting cholinergic system.
81 citations,
February 2014 in “EMBO molecular medicine” Activating Nrf2 in skin cells causes skin disease similar to chloracne in mice.
30 citations,
November 2020 in “Journal of Advanced Research” Conditioned medium from keratinocytes can improve hair growth potential in cultured dermal papilla cells.
11 citations,
August 2021 in “Aging” Collagen and TGF-β2 help maintain hair cell shape and youthfulness.
3 citations,
January 2020 in “Clinical dermatology review” Trichoscopy is useful for diagnosing hair and scalp disorders in people with darker skin.
1 citations,
April 2023 in “Biomaterials advances” Gellan gum hydrogels help recreate the environment needed for hair growth cell function.
22 citations,
March 2021 in “Materials Today Bio” Scaffold-based strategies show promise for regenerating hair follicles and teeth but need more research for clinical use.
January 2023 in “Indian journal of ophthalmology. Case reports” A woman lost vision in one eye after a forehead injection, but prompt treatment led to partial vision recovery.
701 citations,
August 2014 in “Nature medicine” Alopecia areata can be reversed by JAK inhibitors, promoting hair regrowth.
665 citations,
April 2016 in “Nature communications” Blocking specific proteins can help remove aging cells and might treat age-related diseases and promote hair growth.
546 citations,
February 2008 in “PLANT PHYSIOLOGY” OsPHR2 gene causes excessive phosphate in rice shoots, affecting plant growth and root development.
321 citations,
January 2012 in “Cell stem cell” TGF-β2 helps activate hair follicle stem cells by counteracting BMP signals.
286 citations,
June 2012 in “Nature Immunology” Hair follicles help attract immune cells to the skin during stress.
245 citations,
October 2015 in “Nature medicine” Hair follicle-derived IL-7 and IL-15 are crucial for maintaining skin-resident memory T cells and could be targeted for treating skin diseases and lymphoma.
232 citations,
January 2002 in “Mechanisms of development” Different enzymes are active in different parts of developing mouse organs.
222 citations,
August 2014 in “Cell Metabolism” Mitochondrial Complex I reduces inflammation and increases bone breakdown by affecting certain immune cells.
214 citations,
April 2017 in “Cell” Different small areas within hair follicles send specific signals that control what type of cells stem cells become.
181 citations,
February 2019 in “Cell” Innate lymphoid cells help control skin bacteria by regulating sebaceous glands.
170 citations,
November 2007 in “The journal of investigative dermatology/Journal of investigative dermatology” Skin can heal wounds without hair follicle stem cells, but it takes a bit longer.
169 citations,
February 2018 in “Immunity” Inactive stem cells in hair follicles and muscles can avoid detection by the immune system.
164 citations,
February 2010 in “Journal of Cell Science” Human dermal stem cells can become functional skin pigment cells.
149 citations,
June 2010 in “The FASEB journal” miR-31 regulates hair growth by controlling gene expression in hair follicles.
136 citations,
July 2014 in “Proceedings of the National Academy of Sciences of the United States of America” FGF5 gene mutations cause unusually long eyelashes by affecting hair growth regulation.
132 citations,
September 2009 in “Experimental Dermatology” A reliable system was developed to distinguish hair growth stages, aiding in identifying hair growth promoters or inhibitors.
127 citations,
January 2008 in “PloS one” Vitamin D receptor helps control hair growth and could be used to treat certain skin tumors.
109 citations,
February 2018 in “CB/Current biology” ERULUS controls root hair growth by regulating cell wall composition and pectin activity.