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Finasteride, a drug used for certain conditions, can cause serious side effects like sexual dysfunction, suicidal thoughts, and increased diabetes risk, and there's a need for more awareness and research about these effects.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

Stress can worsen skin and hair conditions by affecting the skin's immune response and hormone levels.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

GABRA2 gene variations impact alcohol response, and hair loss medication finasteride reduces some effects.

Flutamide effectively reduced excessive hair growth and improved related symptoms in hirsutism patients without significant side effects.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

New genes and pathways are important for testosterone production and male sexual development.

New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.

Cyclosporin A helps mice grow hair by blocking a specific protein activity in skin cells.

Finasteride affects alcohol intake in male mice, possibly due to neurosteroids.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.

New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.

Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.

The mineralocorticoid receptor may play a role in skin and hair health and could be a new target for treating related disorders.

Adrenal disorders can cause lasting brain and behavior issues in children.

The review suggests younger men taking 1 mg finasteride report more side effects, including sexual, skin, metabolic, and psychological issues.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

Finasteride reduces alcohol withdrawal severity in male mice but increases it in female mice.

Sex hormones affect brain injury differently in males and females.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Recent genetic insights show that low-renin hypertension includes a range from essential hypertension to secondary or familial forms, affecting diagnosis and treatment.

New compounds may soon be tested to treat excessive hair growth in women.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

Pregnancy reduces anxiety in rats, but finasteride reverses this effect.

Finasteride can cause sexual problems and depression in young men.

Consider benefits and risks of new alopecia treatments for safety.

Finasteride blocks progesterone's effect on absence seizures in rats.