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Increased HIF-1α is linked to the inflammation and severity of hidradenitis suppurativa, suggesting treatments that lower HIF-1α could help.

The vitamin D receptor helps maintain hair and bone health even without binding vitamin D.

Pregnancy right after giving birth in mice lacking IL-10 causes milk that leads to liver issues and hair loss in their babies.

Eurycoma longifolia extract may help increase testosterone levels and reduce andropause symptoms.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Mice without the vitamin D receptor gene lose hair due to disrupted hair follicle cycles.

New treatments for male hypogonadism are effective and should be personalized.

Cytokines and neuropeptides are key in controlling androgen levels, affecting skin and hair conditions.

The Androgen Receptor could be a target for treating diseases like cancer, but more research is needed to confirm the effectiveness of potential treatments.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

Father's finasteride use may affect son's fertility and testicular function.

TRM21 helps control flavonoid production and root hair growth in Arabidopsis thaliana.

The document explains various skin conditions and their treatments.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.

Male pattern hair loss is genetic and influenced by hormones, with treatments like minoxidil and surgery available.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

A girl with rickets and hair loss was found to have a rare condition where her body didn't respond to vitamin D treatment.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

A 3-month stay in space causes skin thinning, disrupts hair growth, and changes muscle-related genes in mice.

Understanding the genetics of rare inherited ichthyosis syndromes is key for better treatments and genetic counseling.

Eating high glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

The review found no clear link between vitamin D receptor gene variations and polycystic ovary syndrome.