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Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

The conclusion is that accurately identifying the cause of high androgen levels in women with PCOS is crucial and requires specific tests.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Low testosterone in men is a risk factor for a specific heart rhythm issue, and testosterone treatment may help prevent it.

Certain genetic markers linked to reproductive potential were identified by their impact on a protein's ability to bind to genes.

Low-dose anti-androgen drugs and certain drug combinations are effective for hirsutism, and insulin sensitizers show promise, especially for those with polycystic ovarian syndrome.

Certain gene variants in estrogen receptors are linked to polycystic ovary syndrome, mainly affecting metabolism, in Tunisian women.

The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.

Certain nutrients can help keep skin healthy as we age.

Polycystic Ovary Syndrome (PCOS) is a hormonal disorder in women that can cause infertility and other health issues, and it may be improved by treatments that increase insulin sensitivity.

Antiandrogens can treat female hormonal conditions, but environmental ones may harm reproductive health.

The patient's high testosterone was reduced by a medication that suppresses gonadotropin.

Hirsutism is often caused by high male hormone levels and can be treated with lifestyle changes and medications.

Alopecia X in dogs is a cosmetic issue, not a hormonal disorder, and harmful treatments should be avoided.

Some antiandrogens may lower testosterone better than others, but it's unclear which is best for feminization in transgender women; more research is needed.

AC5 improves hair loss and hair quality with high satisfaction rates.

Combination therapies for androgenetic alopecia work best but can have significant side effects and costs.

Understanding how androgens and their receptors work can lead to improved treatments for skin diseases.

New tools show that in fish, NPY increases feeding and somatostatin decreases it.

Macrophage iron release is crucial for hair growth and wound healing.

Isotretinoin can cause serious birth defects and needs careful use, especially in pregnant women.

Sex and sex hormones can affect brain inflammation in Parkinson's disease, with male mice being more affected and female mice showing a protective effect.

Over a third of women thought to have non-classical congenital adrenal hyperplasia didn't have it confirmed by genetic tests.

The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.

Insulin resistance and high male hormone levels are major causes of Polycystic Ovary Syndrome.

Hirsutism in teen girls is common, usually harmless, but can sometimes signal serious issues and is treatable.

Certain brain hormones and chemicals are linked to the development of Polycystic Ovary Syndrome.

Melatonin, the sleep hormone, can help treat skin conditions like dermatitis, hyperpigmentation, and scalp disorders, and may also aid in skin aging prevention and regeneration. However, it's not recommended for asthma due to its pro-inflammatory effect.

Treating hair loss effectively may require a multi-sided approach, using different treatments together, and topical treatments could be more effective and safer than oral ones.