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    Research 61–90 of 1000+

    1. Exercise activates the PI3K-AKT signal pathway by decreasing the expression of 5α-reductase type 1 in PCOS rats Scientific reports · 2018 · 28 citations
    2. Selected variants of the steroid-5-alpha-reductase isoforms SRD5A1 and SRD5A2 and the sex steroid hormone receptors ESR1, ESR2 and PGR: No association with female pattern hair loss identified Experimental Dermatology · 2012 · 18 citations
    3. The 5alpha-reductase type 1, but not type 2, gene is expressed in anagen hairs plucked from the vertex area of the scalp of hirsute women and normal individuals Brazilian Journal of Medical and Biological Research · 2003 · 17 citations
    4. Effect of C-ring modifications in benzo[c]quinolizin-3-ones, new selective inhibitors of human 5α-reductase 1 Bioorganic & Medicinal Chemistry · 2001 · 12 citations
    5. Changes in serum free testosterone, sleep patterns, and 5‐alpha‐reductase type I activity influence changes in sebum excretion in female subjects Skin research and technology · 2014 · 10 citations
    6. Synthesis and activity of 8-substituted benzo[c]quinolizin-3-ones as dual inhibitors of human 5α-reductases 1 and 2 Bioorganic & Medicinal Chemistry Letters · 2004 · 9 citations
    7. Design, synthesis and biological evaluation of novel androst-3,5-diene-3-carboxylic acid derivatives as inhibitors of 5α-reductase type 1 and 2 Steroids · 2017 · 8 citations
    8. Synthesis and Biological Evaluation of 4-(4-(Alkyl-and Phenylaminocarbonyl)benzoyl)benzoic Acid Derivatives as Non-steroidal Inhibitors of Steroid 5α-Reductase Isozymes 1 and 2 Archiv Der Pharmazie · 2002 · 8 citations
    9. Synthesis of Spiro[cyclohexane-1,2?-[2H]indene] derivatives as inhibitors of steroid 5?-reductase Helvetica Chimica Acta · 1995 · 8 citations
    10. Activity of steroid 4 and derivatives 4a–4f as inhibitors of the enzyme 5α-reductase 1 Bioorganic & medicinal chemistry · 2018 · 3 citations
    11. Hair Growth is Promoted in Mouse Dorsal Skin by a Mixture of <i>Platycladus orientalis</i> (L.) Franco Leaf Extract and Alpha-Terpineol by Increasing Growth Factors and wnt3/β-Catenin Natural Product Communications · 2020 · 2 citations
    12. In silico screening of effective inhibitor of 5α-reductase type 1 for androgenic alopecia treatment Natural Product Research · 2021 · 1 citations
    13. Enabling finasteride 1 mg users to further improve hair pattern: A randomized, double-blind, placebo-controlled trial of a novel product Journal of The American Academy of Dermatology · 2014
    14. Assessment of chemokines MIP-1α and MIP-1 βin Iraqi women with polycystic ovarian syndrome Egyptian Journal of Immunology · 2023 · 1 citations
    15. Different levels of EGF, VEGF, IL‐6, MCP‐1, MCP‐3, IP‐10, Eotaxin and MIP‐1α in the adipose‐derived stem cell secretome in androgenetic alopecia Experimental Dermatology · 2022 · 1 citations
    16. Iron Chelators in the Management of Autoimmune-Induced Alopecia: A Focus on Hypoxia-Inducible Factor 1 Modulation and Hair Restoration Journal of Clinical Medicine · 2025
    17. Referee report. For: Molecular mediators involved in skin healing: a narrative review [version 1; peer review: 1 approved with reservations] Faculty of 1000 Research Ltd · 2022
    18. Different Levels of EGF, VEGF, IL-6, MCP-1, MCP-3, IP-10, Eotaxin and MIP-1𝛼 in Adipose Derived Stem Cells (ADSCs) Secretome in Androgenetic Alopecia 2021
    19. Activity of type 1 5α-reductase is greater in the follicular infrainfundibulum compared with the epidermis British Journal of Dermatology · 1997 · 12 citations
    20. Identification of hepatic molecular mechanisms of action of alpha-tocopherol using global gene expression profile analysis in rats Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 2004
    21. Tumor Necrosis Factor-α and Interleukin-1 Antagonists Alleviate Inflammatory Skin Changes Associated with Epidermal Growth Factor Receptor Antibody Therapy in Mice Cancer Research · 2009 · 53 citations
    22. Benzo[<i>c</i>]quinolizin-3-ones: A Novel Class of Potent and Selective Nonsteroidal Inhibitors of Human Steroid 5α-Reductase 1 Journal of Medicinal Chemistry · 2000 · 28 citations
    23. 3,3-Diphenylpentane skeleton as a steroid skeleton substitute: Novel inhibitors of human 5α-reductase 1 Bioorganic & medicinal chemistry letters · 2007 · 13 citations
    24. Formation of actin mesh structures and alpha-smooth muscle actin dynamics in fibroblasts contribute to dermal regeneration in mouse fetus PLoS ONE · 2025 · 1 citations
    25. Network pharmacology and in vivo experimental analysis for validating the antifibrotic potential of Punica granatum leaves against skin scleroderma: the role of oxidative stress, inflammation and TGF-β1/Snail 1/p-Smad 3 signaling pathway Inflammopharmacology · 2026
    26. 457 Impact of alpha-melanocyte-stimulating hormone on mitochondrial function in human dermal fibroblasts Journal of Investigative Dermatology · 2025
    27. Natural Product-InspiredBis(trifluoromethyl) PhenylHydroxycinnamate Derivatives as Promising Nonsteroidal Inhibitorsof Human Steroid 5α-Reductase Type-1: Synthesis, <i>InVitro</i>, and <i>In Silico</i> Studies OPAL (Open@LaTrobe) (La Trobe University) · 2025
    28. 1326 Translation-dependent skin hyperplasia is promoted by type 1/17 inflammation in psoriasis Journal of Investigative Dermatology · 2023
    29. Faculty Opinions recommendation of Effect of 1 mg/day finasteride on concentrations of serum prostate-specific antigen in men with androgenic alopecia: a randomised controlled trial. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · 2007
    30. Extrarenal Expression of 25-Hydroxyvitamin D<sub>3</sub>-1α-Hydroxylase<sup>1</sup> The Journal of Clinical Endocrinology & Metabolism · 2001 · 845 citations