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The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

Air pollution worsens skin diseases and aging by causing inflammation and oxidative stress.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

The document likely offers guidance on treating a woman's excessive hair growth, considering her symptoms and obesity.

Cyproterone acetate is effective for acne but less so for hirsutism and alopecia, with some side effects and quick menstrual cycle recovery after treatment.

JAK inhibitors are effective in treating various immune-related diseases, not just rheumatoid arthritis.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.

Metformin is effective for treating excessive hair growth in women with PCOS and may work better than the standard treatment in some ways.

Hair and wool have complex microscopic structures with microfibrils and varying cystine content.

Spironolactone is a safe and effective treatment for reducing excessive hair growth in women.

Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.

Lower doses of treatments for hirsutism and acne in PCOS are effective and cause fewer side effects.

Effective treatments for male pattern baldness include oral finasteride and topical minoxidil, while topical minoxidil is best for female pattern baldness.

Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

Dextran sulfate was found to be toxic and ineffective for treating HIV.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Matriptase is crucial for keeping epithelial tissues healthy and functioning properly.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

Flutamide effectively reduced excessive hair growth and improved related symptoms in hirsutism patients without significant side effects.

Probiotic bacteria improved skin and hair health in aged mice.

Fat cells in the skin help start healing and form important repair cells after injury.

New compounds were made that block an enzyme linked to breast cancer better than existing treatments.

Minoxidil is the only FDA-approved topical drug for treating male or female pattern hair loss, and other medications like finasteride and dutasteride can also increase hair growth.

Olive oil compounds may help prevent cancer in animals, but human results are mixed.