research Transient Efficacy of Tofacitinib in Alopecia Areata Universalis
Tofacitinib temporarily regrew hair in a man with alopecia, but its effects didn't last.
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research CD4+CD25+FoxP3+ Regulatory Tregs Inhibit Fibrocyte Recruitment and Fibrosis via Suppression of FGF-9 Production in the TGF-β1 Exposed Murine Lung
Special immune cells called Tregs can help prevent lung scarring by blocking a specific growth factor.
research Polycystic Ovary Syndrome in Salvador, Brazil: A Prevalence Study in Primary Healthcare
About 8.5% of women in Salvador, Brazil, have Polycystic Ovary Syndrome.
research Studying the Genetic Predisposing Factors in the Pathogenesis of Acne Vulgaris
Genetics play a role in acne, but how exactly they contribute is not fully understood.
research Doping-Control Analysis of the 5α-Reductase Inhibitor Finasteride: Determination of Its Influence on Urinary Steroid Profiles and Detection of Its Major Urinary Metabolite
Finasteride affects urinary steroid profiles and can potentially hide steroid abuse in sports drug testing.
research Persistent Escalation of Alcohol Consumption by Mice Exposed to Brief Episodes of Social Defeat Stress: Suppression by CRF-R1 Antagonism
Blocking CRF-R1 can reduce alcohol intake in stressed mice.
research Adrenal Disorders and the Pediatric Brain: Pathophysiological Considerations and Clinical Implications
Adrenal disorders can cause lasting brain and behavior issues in children.
research Higher Body Mass Index Is Associated With Greater Severity of Alopecia in Men With Male-Pattern Androgenetic Alopecia in Taiwan: A Cross-Sectional Study
Higher BMI links to worse hair loss in Taiwanese men.
research The Effect of Weight Loss and Treatment with Metformin on Serum Vaspin Levels in Women with Polycystic Ovary Syndrome
Weight loss and metformin don't significantly change vaspin levels in women with PCOS.
research Redefining Hormone Resistance in Prostate Cancer
The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.
research Current Evaluation of Amenorrhea
The document concludes that identifying the cause of amenorrhea is crucial for proper treatment.
research Original Research—Endocrinology: Comparison of the Steady-State Pharmacokinetics, Metabolism, and Variability of a Transdermal Testosterone Patch Versus a Transdermal Testosterone Gel in Hypogonadal Men
The testosterone patch and gel are both effective, but they have different absorption patterns and effects on hormone levels.
research Profile of Tofacitinib Citrate and Its Potential in the Treatment of Moderate-to-Severe Chronic Plaque Psoriasis
Tofacitinib citrate is effective for moderate-to-severe chronic plaque psoriasis but has safety concerns at higher doses.
research Gender-Specific Association of Androgenetic Alopecia with Metabolic Syndrome in a Middle-Aged Korean Population
Female hair loss linked to metabolic syndrome, not in males.
research Hirsutism
Hirsutism is excessive male-pattern hair growth in women, often caused by hormonal imbalances, and requires ongoing treatment to manage.
research Recent Advances in Thiasteroids Chemistry
New sulfur-containing steroid analogs show promise for more targeted medical treatments.
research Vitamin D Receptor Polymorphisms and Polycystic Ovary Syndrome: A Systematic Review
The review found no clear link between vitamin D receptor gene variations and polycystic ovary syndrome.
research An Update on Medical Treatment Options for Hidradenitis Suppurativa
New treatments for a chronic skin condition show promise, but individualized plans are crucial due to varying responses.
research Basics of Androgen Synthesis and Action
Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.
research CD98hc (SLC3A2) Regulation of Skin Homeostasis Wanes With Age
CD98hc's role in skin health decreases with age.
research Autoimmune Disease and Hair Loss
Autoimmune diseases can cause hair loss, and early treatment is important to prevent permanent damage.
research The Effects of Androgens on T Cells: Clues to Female Predominance in Autoimmune Liver Diseases
Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.
research Androgens in Women: Hormone-Modulating Therapies for Androgen-Mediated Cutaneous Disorders
Hormone treatments can help with women's skin and hair disorders, but they need careful monitoring and more research.
research Neuroactive Gonadal Drugs for Neuroprotection in Male and Female Models of Parkinson's Disease
Some hormone-related drugs may protect brain cells in Parkinson's disease differently in men and women.
research Pemphigus and Associated Comorbidities: A Cross-Sectional Study
People with pemphigus are more likely to have conditions like hypothyroidism, inflammatory bowel disease, and diabetes.
research Reproductive Dysfunction in Women with Epilepsy
Epilepsy and certain epilepsy drugs can lead to reproductive problems in women, but changing medication might improve these issues.
research Azasteroids as Inhibitors of Testosterone 5α-Reductase in Mammalian Skin
Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.
research Effects of Subchronic Finasteride Treatment and Withdrawal on Neuroactive Steroid Levels and Their Receptors in the Male Rat Brain
Finasteride treatment changes brain steroid levels and receptors, affecting brain function even after stopping treatment.
research The Influence of Interferon on Healthy and Diseased Skin
Type I interferons play a key role in the development of various skin diseases.
research Use of Insulin-Sensitizing Agents in Patients With Polycystic Ovary Syndrome
Insulin-sensitizing drugs like metformin can help with ovulation, weight loss, and lower testosterone in some women with PCOS.