48 citations,
February 2013 in “Molecular and Cellular Endocrinology” The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.
32 citations,
May 2010 in “Pharmacopsychiatry” Finasteride reduces new brain cells in male mice, possibly causing depression.
21 citations,
May 2021 in “Prostate Cancer and Prostatic Diseases” COVID-19 might worsen symptoms and progression of benign prostatic hyperplasia, possibly due to inflammation and metabolic disturbances in the prostate gland. More research is needed to confirm this.
September 2024 in “Frontiers in Neuroendocrinology” 5-alpha reductase inhibitors may help protect the brain and gut in Parkinson's disease.
Spironolactone with an oral contraceptive improved hair growth in women with hirsutism.
17 citations,
March 2006 in “Journal of Cosmetic Dermatology” Hormonal changes during and after pregnancy can cause hair growth changes and hair loss, with treatments available for some conditions.
8 citations,
July 2017 in “The Journal of Steroid Biochemistry and Molecular Biology” DHT affects testicular development and regulates spermatogenesis in some fish.
8 citations,
January 1987 in “Gynecological Endocrinology” Flutamide, an antiandrogen, has minimal impact on female rat endocrine systems and does not significantly change their reproductive cycles.
3 citations,
September 2016 in “Natural Product Communications” Germacrene analogs, especially 8-Hydroxy germacrene B, are more effective than germacrone at blocking a hormone-related enzyme and could help treat hair loss.
1 citations,
March 2021 in “medRxiv (Cold Spring Harbor Laboratory)” Many males in Jordan misuse oral contraceptive pills for hair growth, muscle gain, and acne treatment.
July 2023 in “Dermatology and Therapy” 5-Alpha Reductase Inhibitors are effective for male hair loss and some skin conditions, but their effectiveness in women and safety concerns require careful use.
185 citations,
August 2020 in “Mayo Clinic Proceedings” Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.
137 citations,
March 2006 in “Cns Drug Reviews” Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.
110 citations,
October 2019 in “Translational Andrology and Urology” More men are getting benign prostatic hyperplasia, and there are many treatments, from medication to surgery, with new methods being developed.
31 citations,
January 2003 in “Dermatology” Steroidogenic isoenzymes may help improve treatments for common hair loss.
29 citations,
May 2010 in “Annals of Pharmacotherapy” Finasteride may help some women with hair loss, but better options exist.
24 citations,
January 2015 in “Annals of Dermatology” Herbal extracts may help hair grow and could be an alternative to synthetic hair loss treatments.
24 citations,
March 2002 in “Expert opinion on investigational drugs” Different anti-androgen medications can help treat excessive hair growth, but the right choice depends on accurate diagnosis.
22 citations,
March 2000 in “Clinics in Dermatology” Many treatments for hair loss lack proper testing and FDA approval, so their effectiveness is uncertain.
18 citations,
December 2010 in “Journal of Trace Elements in Medicine and Biology” Women with AGA have more androstenedione and dihydrotestosterone, less copper and zinc; copper imbalance affects AGA; treatment improves hormones and minerals.
7 citations,
May 2016 in “SpringerPlus” Some breast cancer patients on hormone therapy experience hair loss, and treatments like certain topical inhibitors and supplements may help without harming their cancer prognosis.
6 citations,
September 2012 in “Clinical Interventions in Aging” Honokiol might help reduce male skin aging by maintaining testosterone levels.
5 citations,
September 2009 in “Journal of Complementary and Integrative Medicine” Citrullus colocynthis fruit extract and its compound may help treat enlarged prostate.
4 citations,
August 2021 in “Biomedicine & Pharmacotherapy” 5-alpha reductase inhibitors, like finasteride and dutasteride, may cause depression, but more research is needed to understand why.
3 citations,
February 2021 in “Molecules” A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.
3 citations,
February 2019 in “Journal of Cosmetic Dermatology” The effects of estrogen on human scalp hair growth are unclear and need more research.
2 citations,
June 2022 in “International Journal of Biomedicine” The review suggests a comprehensive approach to treat hirsutism, focusing on hair removal, medication, and managing emotional effects.
1 citations,
December 2023 in “Curēus” Tadalafil is effective for treating urinary symptoms in men with BPH.
May 2024 in “Brazilian Journal of Hair Health” Finasteride and dutasteride may help prevent hair loss but could cause side effects like sexual dysfunction and psychological issues.
204 citations,
May 2014 in “The Journal of Sexual Medicine” Hormone therapy for trans individuals is effective and generally safe in the short term.