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5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

Cystatin M/E strongly inhibits cathepsin V and cathepsin L, important for skin formation.

There are many treatments for permanent hair loss disorders, but their effectiveness varies and there's no clear best option.

Finasteride effectively blocks rat enzymes, but with varying methods and strength.

A very low-calorie ketogenic diet is effective for quick weight loss and improving health in obese patients, with careful management of side effects and maintenance.

Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.

The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.

Treatments for permanent hair loss from scarring aim to stop further loss, not regrow hair, and vary by condition, with partial success common.

Lichen planopilaris is a chronic, scarring hair loss condition with no definitive cure, requiring accurate diagnosis and treatment to manage symptoms.

Antioxidants can benefit skin health but should be used carefully to avoid negative effects.

The genus Sophora has compounds with potential health benefits and could lead to new drugs, but more research is needed to understand their effects and safety.

Sericin hydrogels heal skin wounds well, regrowing hair and glands with less scarring.

Treatments for melanin disorders exist, but more effective options needed.

Inherited ichthyoses cause widespread skin scaling and thickening due to gene mutations.

Oral tofacitinib can significantly improve recalcitrant lichen planopilaris.

Smart biomaterials that guide tissue repair are key for future medical treatments.

Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.

Dermal Papilla cells are a promising tool for evaluating hair growth treatments.

Finasteride reduces hair growth better, but spironolactone has more side effects.

Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.

Jasmonic acid and its derivatives play important roles in plant health and have potential uses in medicine and agriculture.

Both vitiligo and alopecia areata involve an immune response triggered by stress and specific genes, with treatments targeting this pathway showing potential.

Some heart drugs show promise for other conditions, but more research is needed to confirm their effectiveness and safety.

Mushrooms have beneficial properties for skin and hair care products and have great potential for future cosmetic use.

Most dermatologic medications are safe during pregnancy and breastfeeding, but some should be avoided due to potential risks.

Mercuric triflate is an effective catalyst for various organic reactions, working well at room temperature with high yields.

Finasteride slowly binds to 5-alpha-reductase, affecting enzyme stability and inhibitor potency.

Oral dutasteride and topical pimecrolimus can safely and effectively treat Frontal Fibrosing Alopecia, leading to significant hair regrowth.

Cancer can hijack the body's cell repair system to promote tumor growth, and targeting this process may improve cancer treatments.

Some plant-based treatments can help with benign prostatic hyperplasia symptoms, but more research is needed to confirm their safety and effectiveness.