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This study proposes a model suggesting that the ratio of keratin 15 to keratin 14 in epidermal keratinocytes promotes a progenitor state and opposes differentiation, based on insights from both cell culture and transgenic mouse models.

This study characterized the intron-exon organization of human keratin 15 and keratin 19 genes to aid future mutation detection analyses related to potential genetic disorders of keratinization.

This study suggests that using stable isotope analysis on various tissues can effectively reconstruct individual life histories, providing insights into both the individual and broader population from the Romano-Christian period in Egypt.

This study identified the N-(iodopropenyl) derivative 13 as a promising candidate for development as a radioiodinated androgen receptor ligand due to its binding affinity.

This study describes the molecular conformation and intermolecular interactions in the crystalline structure of the compound C24H31BrO4.

This study found that keratin 15 expression is downregulated in hyperproliferative conditions like psoriasis and hypertrophic scars, suggesting it is not compatible with keratinocyte activation.

This study details a 15-year-old girl with secondary amenorrhea and other symptoms who was found to have a pituitary mass causing multiple hormonal deficiencies, diagnosed as lymphocytic hypophysitis.

This study found that the evodiamine derivative 2-16 exhibited the highest antitumor activity and a broad spectrum of activity against various human cancer cell lines, with improved solubility.

This letter discusses azathioprine-induced alopecia and leukopenia potentially linked to NUDT15 polymorphisms, reporting no new clinical results.

In this study, researchers observed that Keratin 15 expression in hair follicles was significantly higher in normal adult men compared to those with androgenetic alopecia.

This study reported that derivatization with 5-butylpicolinic acid improved the sensitivity for detecting testosterone and DHT in saliva using LC-ESI-MS/MS, with minimal interference from the saliva matrix.

In this study, HPH-15, a newly synthesized compound, demonstrated potential in reducing skin fibrosis in a mouse model by targeting underlying pathogenic mechanisms and exhibited a good safety profile, warranting further clinical trials for fibrotic skin disorders like systemic sclerosis.

In this study, researchers found that the gene LRRC15 was overexpressed in dermal papilla cells from balding areas compared to non-balding areas in patients with androgenetic alopecia.

This study suggests that rather than inhibiting IL-15, selectively stimulating IL-15Ra-mediated signaling could be beneficial for managing alopecia areata and possibly other inflammatory hair loss conditions, as IL-15 promoted hair growth and maintained immune privilege in human hair follicles.

This study suggests that immunostaining for Keratin 15 may be a useful tool for differentiating between basal cell carcinoma and trichoepithelioma.

This study reported that IL-15 promotes human hair growth and protects hair follicle immune privilege, potentially stabilizing alopecia areata treatment outcomes when selectively stimulating IL-15Rα signaling.

This study found an increased risk of asthma and allergic rhinitis in individuals with hidradenitis suppurativa.

In this study, researchers identified three molecules in hair that varied with age, suggesting potential markers for aging and targets for cosmetic products.

This study synthesized and verified the structures of Setipiprant's major and minor metabolites, confirming their regio- and enantioselectivity from earlier proposals in a clinical study.

This study found no significant association between the IL-15 genetic polymorphism (rs17015014) and the risk or severity of Alopecia Areata in the examined population.

This study found that a new analytical approach revealed an increased brain pregnenolone level following finasteride treatment in a mouse model, suggesting potential for improved understanding of neurosteroid roles in brain excitability.

This study reports that a new DART-HRMS method can effectively analyze intact hair for drug use timelines, with cocaine detection aligning with forensic standards and identifying multiple drugs from high-resolution data.

This study highlights that while hair follicle cycling is primarily influenced by growth factors like IGF-1 and Wnt signals, the role of cytokines in normal human hair growth and cycling is less understood.

This study demonstrated radiocalcium uptake in skin, eye, cartilage, and mucous glands, with the highest concentration in the hair follicle's keratogenous zone.

This study demonstrated that a metric based on rotational echo intensity in 2H magic-angle spinning NMR can derive kinetic information for conformational exchange without complex modelling, achieving activation barriers consistent with prior findings.

This study concluded that neither basal nor ACTH-stimulated 17-OHP concentrations effectively indicate carrier status for 21-hydroxylase deficiency among Slovenian hyperandrogenic women, recommending molecular analysis of the CYP21 gene for reliable screening.

In this study, researchers developed a new prostate cancer imaging agent, a [99m Tc]tricarbonyl complex derived from finasteride, which demonstrated high radiochemical purity and significant uptake in the prostate of a rat model, suggesting its potential for noninvasive prostate cancer imaging.

A new antiandrogen compound was made and its detailed three-dimensional shape was described.

In this study, the synthesis of C-4 and C-6 bridged haptens of 11 alpha-hydroxyprogesterone revealed an unexpected formation of a C-4 substituted product using a 6-bromo derivative, contrary to prior reports.

The K15 promoter effectively targets stem cells in the hair follicle bulge.