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This article discusses the role of androgens in metabolic and reproductive health and reports no new experimental results; the focus is on androgen receptor activation by testosterone and 5α-dihydrotestosterone.

This research found that a novel dehydroepiandrosterone derivative (12) significantly reduces cell viability and increases apoptosis in testosterone-stimulated normal and tumor prostate cells, unlike finasteride and dutasteride, which also showed activity under dihydrotestosterone stimulation.

This study found that silicone oil-in-water nanoemulsions using nonionic surfactants can enhance silicone oil absorption on hair, suggesting a promising method for hair care applications.

This review outlines a diagnostic approach for identifying non-PCOS pathology in women with androgen excess, emphasizing the importance of clinical history and biochemical phenotyping but reports no new clinical results.

Evaluate and manage androgen excess in women with a systematic approach, considering both physical and psychological impacts.

This study found that hair steroid profiling is a feasible, non-invasive alternative to serum analysis in adolescents, with androgen levels correlating more strongly with body size and composition in boys than girls.

This review discusses alternative androgen pathways, including the "backdoor" pathway and pathways to 11-oxygenated steroids, and reports no new clinical results; the authors aim to clarify these concepts for better patient treatment.

This review discusses guidelines for acitretin use in dermatology, reporting its efficacy in severe psoriasis and recommendations for combination therapies, without providing new clinical trial results.

This article reviews cyclosporine's mechanism, uses, and dosing in dermatology, but reports no new clinical findings, focusing instead on helping dermatologists integrate it safely into their practice.

This study describes a method to create keratin hydrogels with adjustable erosion rates by mixing different ratios of keratose and kerateine, enabling controlled release of therapeutic agents like insulin-like growth factor 1.

This study developed a bilayer material combining poly(vinyl alcohol) and bacterial cellulose with a gelatin-poly(vinyl alcohol) hydrogel, showing strong potential as a wound dressing due to its good antibacterial properties, cell viability, and sustained drug release.

The Dfl mutation in mice causes poor sebaceous gland function and complete hair loss.

Injecting lentiviral vectors into early gestation mice effectively targets skin stem cells for potential gene therapy.

This study found that ECMs from papillary and dermal papilla fibroblasts support normal basement membrane formation, suggesting potential improvements for therapeutic biomaterials in skin engineering.

This study found that vitamin D receptor activation in primary keratinocytes can occur independently of the 1,25-dihydroxyvitamin D₃ ligand, likely through interaction with retinoid X receptors.

This study found that the patchwork mutation in mice affects melanocyte survival in hair follicles, leading to a variegated coat pattern without partially pigmented hairs due to a community effect among melanoblasts.

This review discusses mesenchymal stromal cell-conditioned medium for various skin conditions and found improvements in wound healing, hair restoration, and more, but emphasizes the need for further research to validate these findings.

This study highlights a scarcity of data and treatment guidelines for vitiligo in Africa, the Middle East, and Latin America, emphasizing the need for regional epidemiological studies and tailored management approaches.

This study highlights rapid advances in alopecia areata treatment following the identification of genetic variants associated with increased disease risk, suggesting potential for precision medicine approaches.

This review discusses treatment options for androgenetic alopecia, highlighting the need for personalized, evidence-based approaches but reports no new clinical results.

This study found that Hirosaki hairless rats experience transient activation of STAT5A in the mammary glands during early lactation, involving O-GlcNAc modification rather than Tyr-phosphorylation.

This study found that Argan press cake extracts stimulated hair growth and reduced inflammation and oxidative stress in human hair follicle dermal papilla cells, suggesting potential for anti-hair loss drug development.

This study found that in mice, low-dose irradiation causes stem cells in hair follicles to undergo chromatin alterations, which may eventually lead to long-term functional loss in tissues or organs.

In this study, hUCMSCs-Exo significantly accelerated wound healing in rat perianal fistulas with notable safety, potentially through the activation of the HIF-1α/TGF-β/Smad signaling pathway.

This report describes the clinical presentation of Papillon-Lefèvre syndrome in two brothers and reviews the related literature, without providing new clinical outcomes.

This review discusses the use of nanomaterials in cosmetics, highlighting their benefits like enhanced stability and skin penetration, while also noting potential health risks and the role of natural ingredients in formulations.

This study explored the wound healing potential of a natural marine soft coral-derived nanoparticle-based gel in a diabetic excision wound model, finding it effectively regulates proinflammatory cytokines and inhibits enzymes related to wound healing.

This study found that a novel bioceramic/alginate hydrogel with photothermal properties and multiple ion release effectively reduces infection and inflammation, and enhances osseointegration in early-stage peri-implant lesions, potentially improving dental implant survival rates.

The authors concluded that incorporating routine endocrinology consultations into transplant care could address CNI-related endocrine toxicities, but prospective studies are needed to assess the impact on graft and patient survival.

This study found that 11-oxygenated androgens were higher in women with PCOS compared to those with idiopathic hirsutism, with no difference from controls, and higher Bisphenol A levels in obese women with PCOS may worsen metabolic issues.