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Women with PCOS are more likely to have impaired glucose tolerance and type 2 diabetes, especially if they are Asian or obese.

The document concluded that more research is needed to understand how estrogen affects the enzyme involved in hirsutism development.

Topical therapies show promise for hair loss and acne treatment with minimal side effects.

New treatments for hair loss should target eight main causes and use specific plant compounds and peptides for better results.

The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.

Oxidative stress worsens PCOS by damaging cells and disrupting metabolism, suggesting antioxidant treatments might help.

Sebocytes play a key role in controlling androgen levels in human skin.

Finasteride's two formulations absorb similarly, showing bioequivalence.

Putting ketoconazole on the skin can help mice grow hair.

Adolescents with PCOS have higher levels of certain androgens, which are linked to hair growth but don't help diagnose PCOS better than testosterone levels.

Hair analysis can help diagnose adrenal disorders non-invasively.

Finasteride negatively affects fish reproduction and gonadal development.

The method can measure multiple steroids in human hair to study long-term steroid metabolism, especially in newborns and children.

DHT affects testicular development and regulates spermatogenesis in some fish.

Testosterone therapy can modestly improve sexual function in menopausal women but should be used cautiously and is not recommended for routine measurement in sexual dysfunction or hirsutism.

Testosterone in older women can increase bone density, muscle mass, fat mass, improve memory, and boost libido, but may cause nipple color changes.

Changes in gut bacteria can contribute to the development of Polycystic Ovary Syndrome (PCOS), affecting metabolism, immunity, and causing inflammation. Treatments may involve adjusting these factors.

The research suggests that the ZP4 gene is linked to egg development in women with PCOS but requires more study to understand its role in infertility.

Finasteride exposure harms tadpole reproduction and hormone balance.

The document concludes that a systematic approach is crucial to identify causes of androgen excess in women beyond the most common cause, Polycystic ovary syndrome (PCOS).

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Diagnosing PCOS is challenging due to its complex and varied symptoms.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.

Diagnosing Polycystic Ovary Syndrome is hard due to varying symptoms, no set criteria, and the need for better tests and education.

Finasteride may cause lasting sexual and mental health issues, and genetic screening could help prevent them.

Androgenic alopecia is mainly caused by DHT, and new treatments focus on hair regeneration and aging factors.

Finasteride affects frog testes by increasing testosterone, decreasing 5α-DHT, and impacting genes related to reproduction and other functions.

A plant extract was found to effectively block an enzyme related to male hormone-related diseases.

Herbal nano-formulations show potential for effective skin delivery but need more research.

Mutations in the enzyme don't significantly change how it binds to its specific substances.