research Targeting Neurosteroid Synthesis as a Therapy for Schizophrenia-Related Alterations Induced by Early Psychosocial Stress
A drug improved schizophrenia-like symptoms in stressed rats by changing brain steroid levels.
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research 5α-Reductase Inhibitors Alter Steroid Metabolism and May Contribute to Insulin Resistance, Diabetes, Metabolic Syndrome, and Vascular Disease: A Medical Hypothesis
Some hair loss and prostate drugs might increase the risk of diabetes and heart disease.
research Steroid 5α-Reductase as a Novel Therapeutic Target for Schizophrenia and Other Neuropsychiatric Disorders
S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.
research Skin Manifestations of Insulin Resistance: From a Biochemical Stance to a Clinical Diagnosis and Management
Certain skin conditions can indicate insulin resistance and should prompt lifestyle changes and medical treatment to manage underlying health issues.
research Androgen Receptor in Rat Liver: Characterization and Separation from a Male-Specific Estrogen-Binding Protein
Male rats have androgen receptors in their liver, which are different from proteins that bind estrogen.
research Scleroderma and L-Tryptophan: A Possible Explanation of the Eosinophilia-Myalgia Syndrome
Taking L-tryptophan supplements might cause a condition similar to scleroderma in some people, which can get better after stopping the supplement and starting corticosteroid therapy.
research The 5-Alpha Reductase Inhibitor Finasteride Reduces Dyskinesia in a Rat Model of Parkinson’s Disease
Finasteride reduces movement issues in Parkinson's disease rats.
research Criteria for Defining Polycystic Ovary Syndrome as a Predominantly Hyperandrogenic Syndrome: An Androgen Excess Society Guideline
Polycystic Ovary Syndrome should be seen mainly as a condition of excess male hormones, with a focus on this in its definition.
research Clinical Characterization of Men with Long QT Syndrome and Torsades de Pointes Associated with Hypogonadism: A Review and Pharmacovigilance Study
Low testosterone in men is a risk factor for a specific heart rhythm issue, and testosterone treatment may help prevent it.
research Phase-Specific Differential Regulation of Mechanical Allodynia in a Murine Model of Neuropathic Pain by Progesterone
Progesterone initially worsens but later reduces neuropathic pain in mice, through different mechanisms.
research Levodopa-Induced Skin Disorders in Patients with Parkinson's Disease: A Systematic Literature Review
Levodopa for Parkinson's disease might be linked to skin issues like melanoma, but it's unclear if the drug or the disease causes them.
research Translational Research in the Generation of Therapeutic Medicine for Wound Healing: A Review
New therapies show promise for wound healing, but more research is needed for safe, affordable options.
research Melatonin And Hair Physiology: Reasons And Clinical Efficacy Data As A Topical Treatment Of Androgenic Alopecia
Melatonin applied to the scalp helps increase hair density in people with early hair loss.
research Candidate SNP Markers of Reproductive Potential Predicted by Significant Change in Affinity of TATA-Binding Protein for Human Gene Promoters
Certain genetic markers linked to reproductive potential were identified by their impact on a protein's ability to bind to genes.
research Vitamin D Receptor: Molecular Signaling and Actions of Nutritional Ligands in Disease Prevention
Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.
research Proline-Rich Protein-Like PRPL1 Controls Elongation of Root Hairs in Arabidopsis Thaliana
A gene in Arabidopsis thaliana, AtPRPL1, affects root hair length but not cell wall composition.
research Medical Treatment of Hirsutism in Women
Treating hirsutism in women often requires a mix of medications and cosmetic methods for best results.
research Alopecia Areata Universalis After Phenobarbital-Induced Anticonvulsant Hypersensitivity Syndrome
A 3-year-old boy lost all his hair due to a rare reaction to phenobarbital, but it grew back after steroid treatment.
research Calcineurin-Based Immunosuppression in Renal Transplantation: Focus on Efficacy, the Role of Steroids, and Cardiovascular Risk
Tacrolimus causes fewer acute rejections than cyclosporin A in kidney transplants but doesn't necessarily improve kidney function after one year; cardiovascular risks and side effects vary between the two drugs.
research Polycystic Ovarian Syndrome: A Comprehensive Review of Symptoms, Diagnosis, and Management
PCOS is a complex disorder managed by treating symptoms and requires a team of specialists.
research The Role of Nuclear Hormone Receptors in Cutaneous Wound Repair
Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.
research Androgens in Women: Role in Androgen-Mediated Cutaneous Disorders
Androgens play a complex role in skin conditions like acne and hair loss in women, and normal blood levels don't always show true androgen status.
research Sebaceous Immunobiology: Skin Homeostasis, Innate Immunity Coordination, Inflammatory Response, and Disease Associations
Sebaceous glands play a key role in skin health, immunity, and various skin diseases.
research Hyperandrogenism in Adolescent Girls
The conclusion is that a thorough approach is needed to diagnose and manage hyperandrogenism in teenage girls, recognizing its major psychological and health effects.
research Telogen Effluvium: A Common Form of Hair Loss
Telogen Effluvium is a common, usually reversible hair loss condition, often improved by removing the trigger and possibly treated with various products, though their effectiveness is uncertain.
research Post-Implantation Erythema
Post-implantation erythema is a red skin condition after medical device implantation that sometimes goes away on its own.
research Androgens and Cardiovascular Disease
Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.
research Is Hormonal Treatment Still an Option in Acne Today?
Hormonal treatments are effective as a second-line option for moderate-to-severe acne in females, but should be used with caution due to health risks.
research Defining the Transcriptional Signature of Esophageal-to-Skin Lineage Conversion
Adult esophageal cells can start to become like skin cells, with a key pathway influencing this change.
research Hair Cycle and Alopecia X in Dogs
Alopecia X in dogs is a cosmetic issue, not a hormonal disorder, and harmful treatments should be avoided.