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Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stem cells necessary for hair growth, leading to progressive hair loss.

Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.

SCD1 is crucial for skin health and overall energy balance.

Genetic screening is crucial for accurately diagnosing APS-1 due to its varied symptoms.

Androgens increase a growth factor in hair cells by creating reactive oxygen species, and antioxidants might help treat hair loss.

A gene called HDAC9 might be a new factor in male-pattern baldness.

Topical bexarotene 1% gel might help regrow hair in alopecia areata and is generally safe.

Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

Minoxidil affects collagen-related genes, potentially helping treat fibrosis.

LEF1 interacts with Vitamin D Receptor, affecting hair follicle regeneration and this could be linked to hair loss conditions.

Retinoic acid, glucocorticoids, and IGF1 increase IGFBP-3 production in human dermal papilla cells, affecting hair growth.

Frontal fibrosing alopecia is linked to increased immune system activity and reduced stem cells, suggesting early treatment targeting this pathway might prevent hair follicle damage.

Thioredoxin reductase 1 does not affect glucocorticoid receptor activity in hair follicle cells.

Mice without certain skin proteins had abnormal skin and hair development.

Finasteride improves surrounding scalp hair and increases hair density after hair transplant.

Exercise improves insulin sensitivity and hormone regulation in PCOS rats.

New anti-acne medications are being tested to offer alternatives to current treatments.

PBX1 helps hair stem cells grow and change by turning on certain cell signals and preventing cell death, which may be useful for hair regrowth treatments.

Arab APS1 patients have unique and recurrent AIRE gene mutations.

People with myotonic dystrophy type 1 have a higher chance of getting skin tumors, including melanoma.

A mutation in the Soat1 gene causes hair structure defects and other health issues in AKR/J mice.

Finasteride improves surrounding scalp hair and increases hair density after hair transplant.

Rice bran extract might help prevent hair loss.

Avicequinone C, a compound found in the Avicennia marina plant, can reduce hair loss by inhibiting a hormone linked to androgenic alopecia.

DA-9401 helps protect rat testis from finasteride damage.

Patients with myotonic dystrophy often have skin problems that suggest early aging and vitamin D issues, and the severity of these problems is linked to their genetic condition and vitamin D levels.

Increased HSD11B1 enzyme expression is linked to higher body fat and insulin resistance.

Certain proteins and their receptors are more active during the growth phase of human hair and could be targeted to treat hair disorders.

VDUP1 is found in skin and hair follicles, interacts with sciellin, and may help regulate skin cell differentiation.

The gene SDR5A1 is found in scalp hair of both hirsute and normal individuals, but it does not explain differences in hair growth.