research Procyanidin Oligomers Counteract TGF-β1- and TGF-β2-Induced Apoptosis in Hair Epithelial Cells: An Insight into Their Mechanisms
Procyanidin compounds from apples and barley promote hair growth and prevent hair cell death.
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research Itraconazole in the Treatment of Acute and Recurrent Vulvovaginal Candidosis: Comparison of a 1-Day and a 3-Day Regimen
A 1-day or 3-day itraconazole treatment is effective for acute vulvovaginal candidosis, but recurrent cases may need longer treatment.
research A Functional Polymorphism in Interleukin-1α (IL1A) Gene Is Associated with Risk of Alopecia Areata in Chinese Populations
A certain genetic variation in the IL1A gene may lower the risk of a hair loss condition in Chinese people.
research Use of H-1 Antihistamine in Dermatology: More Than Itch and Urticaria Control: A Systematic Review
H-1 antihistamines may help with various skin conditions, but more research is needed to confirm their effectiveness.
research Cyclohex-1-Ene Carboxylic Acids: Synthesis and Biological Evaluation of Novel Inhibitors of Human 5α Reductase
Scientists made new substances that can block an enzyme linked to prostate issues and hair loss, with potential for creating a new treatment.
research 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitors for the Treatment of Type 2 Diabetes
Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.
research PBX Homeobox 1 Enhances Hair Follicle Mesenchymal Stem Cell Proliferation and Reprogramming Through Activation of the AKT/Glycogen Synthase Kinase Signaling Pathway and Suppression of Apoptosis
PBX1 helps hair stem cells grow and change by turning on certain cell signals and preventing cell death, which may be useful for hair regrowth treatments.
research 5α-Reductase Type 1 Inhibition of Oryza Sativa Bran Extract Prepared by Supercritical Carbon Dioxide Fluid
Rice bran extract might help prevent hair loss.
research Avicequinone C Isolated from Avicennia Marina Exhibits 5α-Reductase Type 1 Inhibitory Activity Using an Androgenic Alopecia Relevant Cell-Based Assay System
Avicequinone C, a compound found in the Avicennia marina plant, can reduce hair loss by inhibiting a hormone linked to androgenic alopecia.
![Effect of C-Ring Modifications in Benzo[c]quinolizin-3-ones, New Selective Inhibitors of Human 5α-Reductase 1](/images/research/c687900f-ea40-4de1-8f0b-a5b818951b1c/small/15452.jpg)
research Effect of C-Ring Modifications in Benzo[c]quinolizin-3-ones, New Selective Inhibitors of Human 5α-Reductase 1
Changing the C-ring structure in certain compounds can make them better at blocking a specific human enzyme.
research Evaluation of Bioequivalence of Five 0.1 mg Dutasteride Capsules Compared to One 0.5 mg Dutasteride Capsule: A Randomized Study in Healthy Male Volunteers
Taking five small dutasteride capsules is the same as taking one larger capsule.
research Ruxolitinib Rescues Multiorgan Clinical Autoimmunity in Patients With APS-1
Ruxolitinib significantly improves multiple autoimmune conditions in APS-1 patients.
research Lichen Planopilaris: Demographic, Clinical and Histopathological Characteristics and Treatment Outcomes of 25 Cases
Lichen planopilaris can be accurately diagnosed and effectively treated.
research Myotonic Dystrophy Type 1: Enhancing Patient Management Through Genetic and Multisystem Studies
There is no cure for myotonic dystrophy type 1, so treatment focuses on managing symptoms and complications.
research The Evaluation and Management of Hirsutism
Most women with excess hair growth have an underlying hormonal issue, often treated with medication and hair removal methods.
research Randomized Clinical Trial Comparing 5% and 1% Topical Minoxidil for the Treatment of Androgenetic Alopecia in Japanese Men
5% minoxidil works better for hair growth than 1% minoxidil.
research Persistent Sexual Dysfunction with Finasteride 1 mg Taken for Hair Loss
Finasteride for hair loss increases risk of long-lasting sexual dysfunction.
research Oral Isotretinoin Combined with Topical Clobetasol 0.05% and Tacrolimus 0.1% for the Treatment of Frontal Fibrosing Alopecia: A Randomized Controlled Trial
Taking oral isotretinoin with creams worked better for treating a type of hair loss than creams alone.
research A Prospective, 1-Year Trial Using Saw Palmetto Versus Finasteride in the Treatment of Category III Prostatitis/Chronic Pelvic Pain Syndrome
Finasteride improves chronic pelvic pain, saw palmetto doesn't.
research Synthesis and In Vitro Evaluation of 4-Substituted N-(1,1-Dimethylethyl)-3-Oxo-4-Androstene-17β-Carboxamides as 5α-Reductase Inhibitors and Antiandrogens
The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.
research Decline of Life’s Energy Theory of Aging: Revitalization of Energy Metabolism and Aging Mitochondria
Boosting mitochondrial energy production with supplements like acetyl-L-carnitine may improve aging-related cellular function and health conditions.
research Androgenic Alopecia Is Associated With Less Dietary Soy, Higher Blood Vanadium, and rs1160312 Polymorphism in Taiwanese Communities
Men with more vanadium in their blood and who drink less soy milk are more likely to have hair loss.
research Comparison of Treatment with Clobetasol Propionate 0.05% and Topical Pimecrolimus 1% in Alopecia Areata
Clobetasol and pimecrolimus are similarly effective for alopecia areata, but pimecrolimus has fewer side effects and is preferred for long-term use.
research Dose-Response Study of Topical Minoxidil in Male Pattern Alopecia
Minoxidil 1% and 2% best promote hair growth and may prevent hair loss.
research The Immunological Impact of IL-1 Family Cytokines on the Epidermal Barrier
IL-1 family cytokines are crucial for skin defense and healing, but their imbalance can cause skin diseases.
research Steroidogenic Factor-1 Lineage Origin of Skin Lesions in Carney Complex Syndrome
Skin lesions in Carney Complex are caused by a gene change in some skin cells that leads to increased pigmentation and may lead to tumors.
research Hair Growth Effects of Laminaria Japonica Extract and Growth Factor Mixture on a C57BL/6 Mouse Model
Laminaria japonica extract with IGF-1 improved mouse hair growth and could be a potential alopecia treatment.
research Investigation of the Role of SIRT3, SIRT7, NFATC1, and PDL-1 Genes in Androgenetic Alopecia
SIRT3 and SIRT7 genes may play a role in hair loss.
research Contribution of Hair Density and Hair Diameter to the Appearance and Progression of Androgenetic Alopecia in Japanese Men
Hair thickness matters more than density for baldness in Japanese men over 25.
research Hair Counts in Scalp Biopsy of Males and Females with Androgenetic Alopecia Compared with Normal Subjects
AGA patients have fewer hairs and smaller follicles; T:V ratio above 4:1 may indicate AGA.