32 citations,
January 2005 in “Journal of The American Academy of Dermatology” Some babies are born with alopecia areata, and a treatment with clobetasol propionate can regrow hair in half of the cases.
24 citations,
July 1987 in “Dermatologic Clinics” Systemic diseases can cause hair loss, which is often reversible with treatment.
January 1982 in “Side effects of drugs annual” High doses of certain vitamins can cause serious side effects and health risks.
236 citations,
July 2001 in “Trends in Molecular Medicine” Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.
30 citations,
May 2004 in “Journal der Deutschen Dermatologischen Gesellschaft” The document concludes that early diagnosis and treatment are crucial for children with hair loss to prevent permanent damage, although not all conditions can be effectively treated.
5 citations,
January 2016 in “Asian pacific Journal of Tropical Biomedicine” Phthirusa pyrifolia extract may lower testosterone and harm male rat reproduction without damaging the liver or kidneys.
4 citations,
August 2013 in “Expert Review of Dermatology” Updated treatments for female hair loss include minoxidil, antiandrogens, hair transplants, and light therapy.
1 citations,
October 2018 in “InTech eBooks” Only minoxidil and finasteride are FDA-approved for hair loss, with other treatments available but less effective or with side effects.
January 2009 in “Springer eBooks” The document concludes that managing skin conditions during pregnancy is important and requires specialized care.
3 citations,
April 2021 in “Cureus” Low Vitamin D is common in people with Alopecia Areata, but its impact on the condition needs more research.
138 citations,
June 2004 in “Journal of Investigative Dermatology” Involucrin gene expression is controlled by specific proteins and signaling pathways.
March 2021 in “AACE clinical case reports” A man with both Klinefelter syndrome and primary hyperparathyroidism showed a rare combination of symptoms and genetic patterns.
185 citations,
February 2018 in “Journal of Investigative Dermatology” Melatonin may benefit skin health and could be a promising treatment in dermatology.
July 2023 in “Frontiers in Veterinary Science” Melatonin helps hair grow by activating the RORα receptor in goats.
38 citations,
June 2018 in “Archives of Toxicology” Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.
6 citations,
March 2018 in “Proceedings - Baylor University. Medical Center” Sarcoidosis can cause severe high calcium levels, hair loss, and kidney failure.
2 citations,
December 2018 in “Қазақстанның клиникалық медицинасы” Higher Vitamin-D levels may help treat certain types of hair loss.
May 2024 in “Endocrine practice” Vitamin A toxicity can cause serious health issues like hypercalcemia and is often overlooked.
February 2023 in “Clinical, Cosmetic and Investigational Dermatology” Higher leptin and lower vitamin D levels may contribute to male pattern baldness.
44 citations,
June 2017 in “The EMBO Journal” LPA3 signaling in the uterus is crucial for placental formation and fetal development.
October 2024 in “Journal of the Endocrine Society” A rare genetic mutation causes resistance to vitamin D, leading to severe rickets and requiring high doses of calcium and vitamin D for treatment.
June 2024 in “The Journal of Nutritional Biochemistry” 1,25-(OH)2D3 helps hair grow by blocking certain harmful signals.
10 citations,
January 2012 in “Annals of Dermatology” Finasteride 1.25 mg showed small improvements in hair density and thickness for female pattern hair loss, but more research is needed.
19 citations,
May 2020 in “Journal of The American Academy of Dermatology” Low-dose oral minoxidil improves hair growth in male hair loss.
November 2022 in “Journal of the Endocrine Society” Estrogen deficiency can reduce the enzyme activity needed to activate vitamin D.
50 citations,
October 2014 in “International Journal of Clinical Pharmacology and Therapeutics” New finasteride solution effectively reduces baldness-causing hormone, potentially with fewer side effects.
2 citations,
February 2023 in “BMC women's health” Birth control pills change the activity of certain inflammation and blood clotting genes in women with PCOS.
Oral minoxidil is as effective and safe as topical minoxidil for treating female pattern hair loss.
2 citations,
March 2021 in “Journal of Cosmetic Dermatology” Combining platelet-rich plasma therapy with low dose oral minoxidil improved hair growth in men with hair loss, with slightly higher satisfaction at the higher minoxidil dose.
12 citations,
July 1957 in “Journal of Investigative Dermatology” Giving dihydrotachysterol to mother rats caused skin hardening and bone issues in their babies through milk.