research Effect of Neurosteroids on Basal and Stress-Induced Oxytocin Secretion in Luteal-Phase and Pregnant Sheep
Neurosteroids help regulate oxytocin levels, especially during stress and pregnancy, to protect against premature labor.
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research 5α-Reductases in Human Physiology: An Unfolding Story
Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.
research Setipiprant for Androgenetic Alopecia in Males: Results from a Randomized, Double-Blind, Placebo-Controlled Phase 2a Trial
Setipiprant did not significantly improve hair growth in men with hair loss.
research Adverse Effects of the 5-Alpha-Reductase Inhibitor Finasteride on Daphnia Magna: Endocrine System and Lipid Metabolism Disruption
Finasteride harms Daphnia magna's reproduction, growth, and metabolism.
research PBX1 Attenuates Hair Follicle-Derived Mesenchymal Stem Cell Senescence and Apoptosis by Alleviating Reactive Oxygen Species-Mediated DNA Damage Instead of Enhancing DNA Damage Repair
PBX1 helps reduce aging and cell death in hair follicle stem cells by decreasing DNA damage, not by improving DNA repair.
research Regulatory Network of Ginsenoside Biosynthesis Under Ro Stress in the Hairy Roots of Panax Ginseng Revealed by RNA Sequencing
Ro stress hindered ginseng root growth and ginsenoside production, but increased certain hormones and affected gene regulation related to plant growth and stress responses.
research Pregnenolone for the Treatment of L-DOPA-Induced Dyskinesia in Parkinson's Disease
Pregnenolone might help manage movement issues caused by Parkinson's disease treatment without reducing the medicine's effectiveness.
research Use of Finasteride in the Treatment of Men With Androgenetic Alopecia
Finasteride effectively improves hair growth and slows hair loss in men with male pattern baldness.
research The Establishment and Characterization of Immortalized Human Dermal Papilla Cells and Their Hair Growth Promoting Effects
Researchers made a cell line that grows quickly and can help with hair growth research.
research Medical Treatment of Male Pattern Alopecia (Androgenic Alopecia)
Topical minoxidil is the most promising treatment for male pattern hair loss, but more research is needed to confirm its effectiveness and safety.
research The Effects of Minoxidil on Pulmonary and Systemic Hemodynamics in Hypertensive Men
Minoxidil lowers blood pressure and increases heart efficiency, but may raise lung artery pressure in some people.
research Neuroactive Steroids and Ethanol Exposure: Relevance to Ethanol Sensitivity and Alcohol Use Disorders Risk
Neuroactive steroids may affect the risk and treatment of alcohol use disorders.
research Minoxidil in Refractory Hypertension
Minoxidil effectively controls severe high blood pressure in children with few side effects.
research Pseudo Fringe Sign in Frontal Fibrosing Alopecia
Frontal fibrosing alopecia can mimic traction alopecia but has distinct features like facial papules and eyebrow thinning.
research Update on Medical Management of Benign Prostatic Hyperplasia
Castration is preferred for non-breeding male dogs with BPH, but other treatments are available with specific pros and cons.
research Expression of Androgen Receptor Coactivator ARA70/ELE1 in Androgenic Alopecia
The protein ARA70/ELE1 is involved in male pattern baldness, and lower levels of its short form may lead to hair thinning.
research 5α-Reductase Inhibitors
Finasteride effectively treats enlarged prostate and male baldness, improves symptoms of hirsutism in women, but doesn't work for acne, and may delay prostate cancer progression with few side effects.
research A Cross-Sectional Randomized Comparative Study of Topical Minoxidil Solution With and Without Finasteride in Male Pattern Androgenetic Alopecia in South Indian Patients
Adding finasteride to minoxidil solution for hair loss treatment didn't show extra benefits, just increased cost and fear of side effects.
research Is Finasteride Also Effective for Acne Vulgaris?
Finasteride is not expected to be effective for treating Acne vulgaris.
research 5-Alpha-Reductase Deficiency in a Saudi Girl
A Saudi individual initially identified as a girl had a genetic disorder affecting gender development.
research Androgens and Human Hair Growth
Androgens can cause hair growth in some areas and hair loss on the scalp.
research Synthesis and Actions of 5α-Reduced Metabolites of Testosterone in the Nervous System
Testosterone and its metabolites affect brain functions and could help treat neurological disorders.
research A Rare Case of Hereditary 1,25-Dihydroxyvitamin D Resistant Rickets
A rare genetic mutation causes resistance to vitamin D, leading to severe rickets and requiring high doses of calcium and vitamin D for treatment.
research 1,25-(OH)2D3 Promotes Hair Growth by Inhibiting NLRP3/IL-1β and HIF-1α/IL-1β Signaling Pathways
1,25-(OH)2D3 helps hair grow by blocking certain harmful signals.
research Efficacy of Finasteride 1.25 mg on Female Pattern Hair Loss: Pilot Study
Finasteride 1.25 mg showed small improvements in hair density and thickness for female pattern hair loss, but more research is needed.
research Efficacy and Safety of Very-Low-Dose Oral Minoxidil 1.25 mg in Male Androgenetic Alopecia
Low-dose oral minoxidil improves hair growth in male hair loss.
research Estrogen Deficiency as a Cause of Decreased 1-Alpha-Hydroxylase Activity
Estrogen deficiency can reduce the enzyme activity needed to activate vitamin D.
research A Novel Finasteride 0.25% Topical Solution for Androgenetic Alopecia: Pharmacokinetics and Effects on Plasma Androgen Levels in Healthy Male Volunteers
New finasteride solution effectively reduces baldness-causing hormone, potentially with fewer side effects.
research Oral Contraceptive Pill Treatment Alters Gene Expression of Inflammatory Markers in Polycystic Ovary Syndrome Women
Birth control pills change the activity of certain inflammation and blood clotting genes in women with PCOS.
research Randomized Non-Inferiority Study of Oral Minoxidil (1.25 mg/day) vs. 5% Topical Minoxidil in Treating Female Pattern Hair Loss
Oral minoxidil is as effective and safe as topical minoxidil for treating female pattern hair loss.