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research THERAPEUTIC HOTLINE: Genetic variations in the androgen receptor gene and finasteride response in women with androgenetic alopecia mediated by epigenetics

16 citations , March 2011 in “Dermatologic Therapy”

This study suggests that genetic variants in the androgen receptor gene may predict which postmenopausal women with hair loss respond to finasteride therapy.

research Cell Enriched Autologous Fat Grafts to Follicular Niche Improves Hair Regrowth in Early Androgenetic Alopecia

8 citations , February 2020 in “Aesthetic Surgery Journal”

This study found that early male hair loss treatment with Puregraft fat and low-dose adipose-derived regenerative cells increased terminal hair counts at 24 weeks compared to a saline control, indicating promise for androgenetic alopecia treatment.

research Stem cell-derived motor neurons from spinal and bulbar muscular atrophy patients

48 citations , June 2014 in “Neurobiology of Disease”

This study found that stem cells derived from spinal and bulbar muscular atrophy patients exhibited reduced androgen receptor levels and HDAC6, providing potential insights into the disease mechanism for future therapies.

research COVID‐19, androgens, and androgenic alopecia

6 citations , December 2020 in “Dermatological reviews”

This review discusses the potential link between androgenic alopecia, androgens, and the severity of COVID-19, highlighting possible therapeutic targets but reports no new clinical results.

research Polymorphic CAG repeat numbers in the androgen receptor gene of female pattern hair loss patients

10 citations , November 2010 in “Journal of Dermatology”

In this study, the researchers reported that finasteride's efficacy in treating female pattern hair loss in Japanese patients was not predictable based on CAG repeat numbers in the androgen receptor gene.

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Community Join

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community Proof DHT is not the main cause of hair loss. TRPS1 Gene and Protein might be. PP405 won’t work. AMP-303 might!

153 upvotes 6 months ago

Hair loss may be linked to the TRPS1 gene and protein, not just DHT. Amplifica's AMP-303 targets mesenchymal stem cells and shows promise in treating hair loss, unlike Pelage's PP405.

community Severe copper deficiency, and also zinc deficiency. Looking for testimonials.

2 upvotes 9 months ago

A 36-year-old man with androgenetic alopecia suspects copper and zinc deficiencies may be accelerating hair loss and is supplementing copper to address this. He is also monitoring blood sugar levels due to previous prediabetes concerns and plans to test for insulin resistance.

community No longer have drive in the gym

in Chat 8 upvotes 5 months ago

The user lost gym motivation after taking finasteride for four months, possibly due to its effect on DHT levels. Suggestions include adjusting dosage, trying topical treatments, using caffeine, checking testosterone levels, and considering supplements like SSRIs or pregnenolone.

community Finasteride is Good for Heart Health!

in Research/Science 119 upvotes 2 years ago

Finasteride, a hair loss and prostate drug, may also benefit heart health. Some users discuss the potential negative effects of DHT on the heart and the balance between hair loss treatments and heart health.

community I've been afraid to start Finasteride treatment for 5 years, on it for 2 weeks, regret that hadn't started it earlier and here's my story

31 upvotes 4 years ago

A 28-year-old male, losing hair since his teens, started taking 0.31 mg finasteride daily for two weeks with no side effects and regrets not starting earlier. He tried various treatments like minoxidil, scalp massages, and vitamins but found finasteride most effective.

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