May 2026 in “International Journal of Molecular Sciences” This study found that plucked hair follicles can serve as a practical and scalable source for regenerative medicine, as researchers successfully isolated and expanded keratinocytes and mesenchymal stem cells for potential cell-based and cell-free therapies, demonstrating significant wound-healing bioactivity in vitro.
September 2026 in “Wound Repair and Regeneration” This systematic review suggests that stem cell-based therapies may offer potential benefits for healing pure venous ulcers, but findings are preliminary due to small sample sizes and varied interventions.
Stem cell therapies show promise for healing skin wounds but need more testing.
This review reports that exosome-based therapies, coupled with nanotechnology and AI, show promise in aesthetic medicine, notably in skin rejuvenation and hair restoration, but large-scale trials and clearer regulatory frameworks are needed for effective clinical adoption.
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October 2017 in “International Journal of Molecular Sciences” This review examines the challenges of cell engraftment in regenerative medicine and discusses potential strategies to improve the efficacy of cell-based therapies, including cell-free regenerative approaches.