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In this study, autologous platelet-rich plasma improved skin wound healing in mice, associated with reduced inflammation and enhanced angiogenesis and re-epithelialization, but the underlying regulatory mechanism requires further investigation.

This study reported that in a mouse tail wound model, the synthetic dual inhibitor corin accelerated wound closure by enhancing re-epithelialization, and further in vitro experiments demonstrated increased expression of genes promoting keratinocyte migration, suggesting its potential as a treatment for chronic wounds.

This study found that transgenic mice with expression of HPV16 E6/E7 oncogenes showed improved ear tissue regeneration, including hair follicles and cartilage, without tumor formation.

This study found that dendritic epidermal T cells and their exosomes enhance epidermal stem cell proliferation, accelerating wound re-epithelialization in the skin.

This review discusses the role of extracellular vesicles as therapeutic agents for wound healing and highlights the need for further research into their clinical applications.